Biological Activity Assessment of Probiotic-Fermented Red Ginseng Extract-Based Tonic Supplement for Companion Animals and Livestock

다국어 초록 (Multilingual Abstract)

ABSTRACT : This study evaluated the physiological effects of probiotic- and postbiotic-fermented red ginseng extract in Sprague Dawley rats and Hy-Line Brown laying hens to assess its potential as a tonic supplement for animals. Two powder types were prepared using lactic acid bacteria (LAB) cultured in MRS medium (G1) and MRS with red ginseng extract (G2).
In rats, G1 and G2 were administered over 8 weeks. While total cholesterol remained stable, HDL increased (G1: 5.4%, G2: 6.6%) and LDL decreased (G1: 23.6%, G2: 25.1%). Triglycerides also declined (G1: 7.1%, G2: 8.7%). Liver function biomarkers (ALT, AST) showed no toxicity, though ALP levels increased, possibly linked to metabolic or bone-related activity. IGF-1 levels rose slightly, indicating potential growth-promoting effects.
In laying hens, 2% G2 powder was added to feed for 6 weeks. Eggs from treated hens showed improved shell and yolk color, and increases in shell weight (4.5%), yolk weight (5.7%), albumen height (3.6%), and yolk height (5.7%). The Haugh unit, a freshness indicator, improved by 1% over the control.
Overall, the LAB-fermented red ginseng extract demonstrated benefits for lipid metabolism, liver safety, growth, and egg quality. These findings support its potential use as a functional supplement in companion animal and livestock feed.