혈액은행 자동화 장비 도입의 유용성 평가 = Evaluation for the Usefulness of Automated Blood Typing Analyzer

다국어 초록 (Multilingual Abstract)

In this study, we evaluated the usefulness of an automatic blood typing analyzer using QWALYS-2 up (Diagast, Loos Cedex, France). During a month( 01OCT2013 – 31OCT2013) we performed 1,636 tests for ABO & RhD blood typing, 1,374 tests for antibody screen & identification tests and compared the results by automatic blood type analyzer with previous manual methods and column agglutination tests. And we analyzed the economic performance by comparison the test unit price between automatic blood type analyzer and manual methods. In ABO & RhD blood typing tests, there were complete concordances between manual and automated blood typing analyzer for 200 clinical samples. In Antibody screen tests, the concordance rate between manual and automated blood typing analyzer was 98.5% and more strong reaction in automated blood typing analyzer than manual methods. Therefore, the introduction of an automated blood typing analyzer, reagents costs were increased but labor costs were decreased. Considering the importance of transfusion safety and economic advantages, the introduction of an automated blood typing analyzer was very useful.

국문 초록 (Abstract)

본 연구는 혈액은행 자동화 장비 QWALYS-2 up (Diagast, Loos Cedex, France)의 유용성을 평가하기 위하여 수행되었다. 2013년 10월 1일부터 10월 31말까지 1개월간 강원대학교병원 진단검사의학과에 의뢰된 ABO 및 RhD 혈액형 검사 1,636건, 항체선별검사 1,374건을 대상으로 하였고, ABO 및 RhD 혈액형 검사의 평가는 200건을 대상으로 하였다. 혈액은행 자동화장비의 경제성을 평가하기 위해서는 2018년 12월을 기준으로 장비 도입 전인 2013년 1월부터 장비 도입 후 5개년의 ABO 및 RhD 혈액형 검사와 항체선별검사의 단가를 비교하였다. 본 연구의 주요 결과는 ABO 및 Rh 혈액형 검사 결과, 슬라이드나 시험관을 이용한 수기법의 결과가 100% (200/200) 일치하였고 동종항체 선별검사 결과, 불일치 3검체는 수기법으로 재검을 한 결과, 음성을 보여 QWALYS-2 up에서 위양성의 결과를 나타냈으나, 반응의 정도를 비교한 결과 QWALYS-2 up에서 상대적으로 높게 나타났다. 결론적으로 혈액형자동화 장비 도입 전후의 효과를 평가한 결과, 기존의 수기법과 비교하였을 때 높은 일치율을 보였으며, 정확도 면에서도 신뢰할 만한 것으로 판단되었다. 도입 전후의 시약의 비용은 증가하였지만 인건비의 절감을 감안하면 경제적으로도 유용하다고 평가할 수 있다.

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