Transcranial Doppler Ultrasonography를 이용한 편두통의 진단: 예비연구 = Application of Transcranial Doppler Ultrasonography(TCD) for the Diagnosis of Migraine : Preliminary Results

다국어 초록 (Multilingual Abstract)

Dignosis of migraine is only based on the medical history, and objective methods to aid the clinical diagnosisare absent. Although transcranial Doppler ultrasonography (TCD) abnormalities in headache-free migraineurs have been reported previously, diagnostic criteria for migraine is still lacking and this may limit the practication of TCD for migraine. we prospectively studied several abnormal TCD indices in interictal migraineurs and their sensitivity and specificity to define the optimal diagnostic criteria. Young (20 yrs2SD) was observed in 63% of migraineurs while n 12% of control (p<0.01). High Al (<25%) or high I (>3.0) was present I 17% of migraineurs. while 3% and none in controls (p<0.01). Sensitivity of elevated MFV, high Al, and sensitivity and specificity reached 69% and 86%. These preliminary results suggest pathophysiological implication of vasospasm I interictal migraineurs, and TCD may be practically applicable for migraine. Optimal diagnostic criteria and therapeutic options for patients with abnormal TCD findings remain to bo determined.