<P>The optimal timing of percutaneous coronary intervention (PCI) in patients with non–ST-segment elevation myocardial infarction (NSTEMI), complicated by acute decompensated heart failure (ADHF), is unclear. A total of 1,027 patients with...
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https://www.riss.kr/link?id=A107654981
Kim, Min Chul ; Jeong, Myung Ho ; Sim, Doo Sun ; Hong, Young Joon ; Kim, Ju Han ; Ahn, Youngkeun ; Ahn, Tae Hoon ; Seung, Ki Bae ; Choi, Dong-Joo ; Kim, Hyo-Soo ; Gwon, Hyeon Cheol ; Seong, In Whan ; Hwang, Kyung Kuk ; Chae, Shung Chull ; Hur, Seung Ho ; Cha, Kwang Soo ; Oh, Seok Kyu ; Chae, Jei Keon
2018
-
SCOPUS,SCIE
학술저널
1285-1292(8쪽)
0
상세조회0
다운로드다국어 초록 (Multilingual Abstract)
<P>The optimal timing of percutaneous coronary intervention (PCI) in patients with non–ST-segment elevation myocardial infarction (NSTEMI), complicated by acute decompensated heart failure (ADHF), is unclear. A total of 1,027 patients with...
<P>The optimal timing of percutaneous coronary intervention (PCI) in patients with non–ST-segment elevation myocardial infarction (NSTEMI), complicated by acute decompensated heart failure (ADHF), is unclear. A total of 1,027 patients with NSTEMI complicated by ADHF who underwent successful PCI were analyzed using a Korean multicenter registry. All patients were divided into 4 groups by the timing of PCI: group 1 (PCI < 2 hour after admission, n = 149), group 2 (2 to 24 hours, n = 577), group 3 (24 to 72 hours, n = 189), and group 4 (≥72 hours, n = 112). We analyzed the incidences of 12-month mortality, nonfatal myocardial infarction (MI), target-vessel revascularization, and rehospitalization because of HF. The prevalence of ADHF in patients with NSTEMI was 15.2% at initial presentation, and in-hospital mortality was higher in group 1 than in the other groups. There were no significant differences in mortality, nonfatal MI, target-vessel revascularization, or rehospitalization for HF during the 12-month follow-up between groups, regardless of initial PCI timing, except for a higher 12-month mortality in patients who received PCI within 24 hours (vs ≥24 hours) (hazard ratio 1.52, 95% confidence interval 1.09 to 2.29, p = 0.046). Early PCI did not reduce adverse clinical outcomes in patients with NSTEMI complicated by ADHF. Delayed PCI after stabilization may be reasonable in such high-risk patients.</P>