For the estimation of age, the measuring of D/L ratio in racemization of aspartic acid(Asp) in human dentine can be used and it estimates age more accurate than the conventional physiological methods. In the natural state, the optical isomers of amino...
For the estimation of age, the measuring of D/L ratio in racemization of aspartic acid(Asp) in human dentine can be used and it estimates age more accurate than the conventional physiological methods. In the natural state, the optical isomers of amino acid slowly undergo spontaneous, nonenzymatic racemization, so the detectable amount of D-enantiomer will be formed from pure L-isomer in dentine. This fact can be used to determine the age of living human and animals or the age of fossil bones. This study, therefore, was measured D/L ratio of aspartic acid in human dentines to estimate the age of each individual.
The correlation of D/L ratio of aspartic acid with actual age was obtained as follows,
The correlation value between the D/L ratio and the actual age was 0.9886, the standard estimated deviation(σ) was 2.07 years of age and the k(yr??) was 8.0×10??. The actual and the estimated ages coincided in 23% of the cases. The errors of ±1 year were 15%, that of ±2 years wee 40%, ±3 years 15%, ±4 years 4%, respectively. Errors of exceeding 5 years were not obtained.