임상적 천식 소아에서 기관지유발시험 중 관찰되는 두 호흡곤란 지표의 특성 비교 = Comparison on the profiles of a modified Borg scale and the pediatric dyspnea scale during an induced bronchoconstriction in children with clinical asthma

다국어 초록 (Multilingual Abstract)

Purpose: Dyspnea is the cardinal symptom of asthma, but it is difficult to quantify clinically. Although modified Borg (mBorg) scale has been successfully used in adult, but there has been some difficulties to apply in children. Recently, Pediatric Dyspnea Scale (PDS) was adequately designed and has been widely used. The aim of this study is to compare 2 evaluating scales of dyspnea provoked by induced-bronchoconstriction in childhood asthma.
Methods: Seventy-three clinically suspected children with asthma were enrolled in this study. Each ‘fractional exhaled nitric oxide (FeNO)’ was documented. Forced expiratory volume in 1 second (FEV₁), mBorg score and PDS score were recorded during metha-choline provocation test.
Results: Mapping using canonical plot demonstrated global similarity between 2 scales with some distinctive features. Whereas mBorg score showed more diverse categories in low level of dyspnea, PDS score did in medium level of it. A distribution of dyspnea perception score at a 20% decrease in FEV₁ relative to baseline (PS₂₀), a perception score of dyspnea at 20% fall in FEV1 of 2 scales represented similar wide, biphasic feature. Statistical relevance was verified with spearman correlation (R_s=0.903, P<0.001) and Bland-Altman analysis. PS₂₀ of both scores and FeNO had no statistical relationship. While relationship between PS₂₀ by mBorg score and the concentration of methacholine at 20% fall in FEV1 (PC₂₀) was not significant (R_s=0.224, P=0.154), that between PS₂₀ by PDS and PC₂₀ was weak positive (R_s=0.29, P=0.063).
Conclusion: PDS had similar pattern to assess the dyspnea with the mBorg scale suggesting adequacy of PDS in evaluating pediat-ric clinical asthma. We expect these scales to help clinical practice in complementary ways. (Allergy Asthma Respir Dis 2017;5:262-268)

참고문헌 (Reference)

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