Local injections of botulinum toxin A have been reported in the treatment of neurogenic bladder dysfunctions including detrusor sphincter dyssynergia and detrusor overactivity. We reports a case of intradetrusor injection of botulinum toxin type A in ...
Local injections of botulinum toxin A have been reported in the treatment of neurogenic bladder dysfunctions including detrusor sphincter dyssynergia and detrusor overactivity. We reports a case of intradetrusor injection of botulinum toxin type A in acervical cord injured patient with neurogenic overactive detrusor refractory to high dose anticholinergic medication. Botulinum toxin A (200 units) was injected cystoscopically into the detrusor in 40 sites over the bladder with sparing the trigone. Urodynamic studies were performed at baseline, and eight days, four weeks, and eight weeks after intradetrusor injection. There was marked improvement of the urodynamic parameters including maximum cystometric capacity and maximum detrusor pressure after intradetrusor botulinum toxin injection.