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      낭성법랑모세포종, 함치성낭, 치성각화낭의 방사선소견과 Ki-67, PCNA, Cytokeratin 발현과의 연관성에 관한 연구 = Relation of the radiologic findings and labeling index of Ki-67, PCNA and cytokeratin in unicystic ameloblastoma, dentigerous cyst and odontogenic keratocyst

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      https://www.riss.kr/link?id=A82406137

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      다국어 초록 (Multilingual Abstract)

      Purpose : To compare the proliferation potential of the epithelial cells between unicystic ameloblastoma (UA), dentigerous cyst (DC), and odontogenic keratocyst (OKC) and to correlate this proliferation potential with the radiographic features of these three pathoses.
      Materials and Methods : Immunohistochemical expression of PCNA, Ki-67, and cytokeratin as a proliferation marker were assessed for 15 cases of UA, 15 cases of DC, and 15 cases of OKC. The degree of immunochemical expression of three proliferation markers were correlated with the radiographic features, especially cortical expansion (negative and positive) and shape of border (scalloped and round).
      Results : Using PCNA and Ki-67, OKC showed the highest proliferation potential and UA the lowest. Statistically significant differences were found between the OKC and the UA (p.0.05). However, no statistically significant difference was present according to the radiographic features in all pathoses. Using cytokeratin, there was no significant differences of proliferation potential among three pathoses.
      Conclusions : OKC epithelium has the most intense proliferation potential, followed by the dentigeous cyst and then unicystic ameloblastoma. There is no significant relation between the radiographic features and the proliferation potential of epithelium of these three pathoses.
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      Purpose : To compare the proliferation potential of the epithelial cells between unicystic ameloblastoma (UA), dentigerous cyst (DC), and odontogenic keratocyst (OKC) and to correlate this proliferation potential with the radiographic features of thes...

      Purpose : To compare the proliferation potential of the epithelial cells between unicystic ameloblastoma (UA), dentigerous cyst (DC), and odontogenic keratocyst (OKC) and to correlate this proliferation potential with the radiographic features of these three pathoses.
      Materials and Methods : Immunohistochemical expression of PCNA, Ki-67, and cytokeratin as a proliferation marker were assessed for 15 cases of UA, 15 cases of DC, and 15 cases of OKC. The degree of immunochemical expression of three proliferation markers were correlated with the radiographic features, especially cortical expansion (negative and positive) and shape of border (scalloped and round).
      Results : Using PCNA and Ki-67, OKC showed the highest proliferation potential and UA the lowest. Statistically significant differences were found between the OKC and the UA (p.0.05). However, no statistically significant difference was present according to the radiographic features in all pathoses. Using cytokeratin, there was no significant differences of proliferation potential among three pathoses.
      Conclusions : OKC epithelium has the most intense proliferation potential, followed by the dentigeous cyst and then unicystic ameloblastoma. There is no significant relation between the radiographic features and the proliferation potential of epithelium of these three pathoses.

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      참고문헌 (Reference)

      1 "치성각화낭과 법랑모세포종의 임상 및 방사선학적 감별진단" 30 : 249-254, 2000

      2 "치성각화낭과 단방성 법랑모세포종의 감별에 관한 방사선 학적 연구" 25 : 17-25, 1995

      3 "전산화단층사진을 이용한 치성각화낭과 법랑모세포종의 감별진단" 32 : 89-97, 2002

      4 "법랑모세포종과 치성각화낭의 방사선학적 감별진단:CT를 중심으로" 32 : 167-173, 2002

      5 "법랑모세포종과 치성각화낭의 방사선 학적 진단의 정확도 및 판독자간과 판독자내 일치" 26 : 147-152, 1996

      6 "p53 protein and Ki-67 reactivity in epithelial odontogenic lesions. An immunohistochemical study" 24 : 393-397, 1995

      7 "The assessment of cellular proliferation by immunohistochemistry:a review of currently available methods and their applications" 24 : 121-31, 1992

      8 "Quantification of PCNA cells within odontogenic jaw cyst epithelium" 23 : 184-9, 1994

      9 "Proliferating cell nuclear antigen staining in syndrome and nonsyndrome. Odontogenic keratocysts" 81 : 217-220, 1996

      10 "Proliferating cell nuclear antigen and Ki67 immunoreactivity in ameloblastomas" 95 : 213-221, 2003

      1 "치성각화낭과 법랑모세포종의 임상 및 방사선학적 감별진단" 30 : 249-254, 2000

      2 "치성각화낭과 단방성 법랑모세포종의 감별에 관한 방사선 학적 연구" 25 : 17-25, 1995

      3 "전산화단층사진을 이용한 치성각화낭과 법랑모세포종의 감별진단" 32 : 89-97, 2002

      4 "법랑모세포종과 치성각화낭의 방사선학적 감별진단:CT를 중심으로" 32 : 167-173, 2002

      5 "법랑모세포종과 치성각화낭의 방사선 학적 진단의 정확도 및 판독자간과 판독자내 일치" 26 : 147-152, 1996

      6 "p53 protein and Ki-67 reactivity in epithelial odontogenic lesions. An immunohistochemical study" 24 : 393-397, 1995

      7 "The assessment of cellular proliferation by immunohistochemistry:a review of currently available methods and their applications" 24 : 121-31, 1992

      8 "Quantification of PCNA cells within odontogenic jaw cyst epithelium" 23 : 184-9, 1994

      9 "Proliferating cell nuclear antigen staining in syndrome and nonsyndrome. Odontogenic keratocysts" 81 : 217-220, 1996

      10 "Proliferating cell nuclear antigen and Ki67 immunoreactivity in ameloblastomas" 95 : 213-221, 2003

      11 "Prognostic evaluation of ameloblastoma based on histologic and radiographic typing" 47 : 11-5, 1989

      12 "Ki-67 Expression in Dentigerous Cysts, Unicystic Ameloblastomas, and Ameloblastomas arising from Dental Cysts" 28 : 55-58, 2002

      13 "Immunohistochemical evaluation of PCNA and Ki-67 in ameloblastoma" 37 : 193-198, 2001

      14 "Expression of proliferating cell nuclear antigen in ameloblastomas and odontogenic cysts" 34 : 408-412, 1998

      15 "Epithelial cell proliferation in odontogenic keratocysts" 24 : 221-226, 1995

      16 "Do Ki67, S-phase, S G2M and DNA ploidy, evaluated by flow cytometry, reveal locoregional metastasis in oral cavity and oropharynx carcinomas?" 9 : 575-580, 2002

      17 "Detection of cell proliferation in tissue sections" 26 : 677-87, 1993

      18 "Cytokeratin expression in the odontogenic keratocyst" 58 : 862-865, 2000

      19 "Comparative Ki-67 expression and apoptosis in the odontogenic keratocyst associated with orwithout an impacted tooth in addition to unilocular and multilocular varieties" 44 : 841-846, 2003

      20 "A comparative study of epithelial cell proliferation between the odontogenic keratocyst, orthokeratinized odontogenic cyst, dentigerous cyst, and ameloblastoma" 22-26, 2004

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2023 평가예정 해외DB학술지평가 신청대상 (해외등재 학술지 평가)
      2020-01-01 평가 등재학술지 유지 (해외등재 학술지 평가) KCI등재
      2019-03-27 학회명변경 한글명 : 대한구강악안면방사선학회 -> 대한영상치의학회 KCI등재
      2012-04-16 학술지명변경 한글명 : 대한구강악안면방사선학회지 -> Imaging Science in Dentistry KCI등재
      2011-03-29 학술지명변경 외국어명 : Korean Journal of Oral and Maxillofacial Radiology -> Imaging Science in Dentistry KCI등재
      2010-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2008-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2006-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2003-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2002-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2000-07-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.12 0.12 0.11
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.11 0.12 0.217 0.02
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