Immunomodulation by a Malleable Matrix Composed of Fermented Whey Proteins and Lactic Acid Bacteria

다국어 초록 (Multilingual Abstract)

Functional foods and nutraceuticals have gained in popularity over the last 10 years. Among natural healthproducts, whey proteins and fermented milk products are paramount. A malleable protein matrix (MPM), composed of wheyfermented by a lactic acid bacterium, capsular exopolysaccharides, vitamins, minerals, and peptides generated during the fer-mentation process, has the potential to be unique by combining multiple health-promoting components. Forced feeding ex-periments on healthy animals were performed to evaluate the immunomodulatory effect of MPM. Glutathione production, an-consumption was evident as seen by the increased polymorphonuclear cell counts and intracellular glutathione levels. The ab-sence of MPM-specific antibody production indicated a lack of undesirable immune recognition of MPM. The MPM, with itsimmunomodulatory properties, has the potential to be a food substitute or a functional food for maintenance of general im-mune health.

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