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      초음파에 의한 온도상승 가시화용 생체 모의매질 = Tissue Mimicking Phantom for Visualization of Temperature Elevation Caused by Ultrasound

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      https://www.riss.kr/link?id=A101069942

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      다국어 초록 (Multilingual Abstract) kakao i 다국어 번역

      To probe the temperature elevation effect caused by ultrasound, a tissue mimicking phantom was newly suggested. A carrageenan gel was adopted to realize not only the required transparency for visualization but also acoustic characteristics similar to human tissue. To visualize the temperature elevation inside phantom, thermochromic film with a critical temperature of discoloration was introduced. Acoustic characteristics of the tissue mimicking phantom were examined when the concentrations of carrageenan and sucrose changed. As the results, the attenuation coefficient of the phantom could be controlled in the range of 0.44~0.49 dB/cm/MHz, and the acoustic impedance in the range of 1.52~1.77 Mrayls. We could control the acoustic characteristics of the phantom by different concentration of carrageenan and sucrose, and it was possible to examine the temperature elevation caused by ultrasound in the phantom. The suggested method was verified by noninvasively visualizing the temperature elevation due to planar and focused ultrasound using the fabricated phantom.
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      To probe the temperature elevation effect caused by ultrasound, a tissue mimicking phantom was newly suggested. A carrageenan gel was adopted to realize not only the required transparency for visualization but also acoustic characteristics similar to ...

      To probe the temperature elevation effect caused by ultrasound, a tissue mimicking phantom was newly suggested. A carrageenan gel was adopted to realize not only the required transparency for visualization but also acoustic characteristics similar to human tissue. To visualize the temperature elevation inside phantom, thermochromic film with a critical temperature of discoloration was introduced. Acoustic characteristics of the tissue mimicking phantom were examined when the concentrations of carrageenan and sucrose changed. As the results, the attenuation coefficient of the phantom could be controlled in the range of 0.44~0.49 dB/cm/MHz, and the acoustic impedance in the range of 1.52~1.77 Mrayls. We could control the acoustic characteristics of the phantom by different concentration of carrageenan and sucrose, and it was possible to examine the temperature elevation caused by ultrasound in the phantom. The suggested method was verified by noninvasively visualizing the temperature elevation due to planar and focused ultrasound using the fabricated phantom.

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      참고문헌 (Reference)

      1 김명석, "음향감쇠매질 내에서 집속초음파에 의한 온도상승의 가시화" 한국음향학회 33 (33): 21-30, 2014

      2 K. Ju, "Zero-crossing tracking technique for noninvasive ultrasonic temperature estimation" 29 : 1607-1615, 2010

      3 J. Kim, "Visualization of thermal distribution caused by focused ultrasound field in an agar phantom" 50 : 07HC08-, 2011

      4 C. Simon, "Two-dimensional temperature estimation using diagnostic ultrasound" 45 : 1088-1099, 1998

      5 A. Anand, "Three-dimensional spatial and temporal temperature imaging in gel phantoms using backscattered ultrasound" 54 : 23-31, 2007

      6 S. Sapareto, "Thermal dose determination in cancer therapy" 10 : 787-800, 1984

      7 K. Maeda, "The safety use of diagnostic ultrasound in obstetrics and gynecology" 6 : 313-317, 2012

      8 J. Jakobsen, "The safety of ultrasound contrast agents" 15 : 941-945, 2005

      9 K. Meada, "The limitation of the ultrasound intensity for diagnostic devices in the Japanese industrial standards" 33 : 241-244, 1986

      10 J. Lehmann, "The biophysical basis of biologic ultrasonic reactions with special reference to ultrasonic Therapy" 34 : 139-151, 1953

      1 김명석, "음향감쇠매질 내에서 집속초음파에 의한 온도상승의 가시화" 한국음향학회 33 (33): 21-30, 2014

      2 K. Ju, "Zero-crossing tracking technique for noninvasive ultrasonic temperature estimation" 29 : 1607-1615, 2010

      3 J. Kim, "Visualization of thermal distribution caused by focused ultrasound field in an agar phantom" 50 : 07HC08-, 2011

      4 C. Simon, "Two-dimensional temperature estimation using diagnostic ultrasound" 45 : 1088-1099, 1998

      5 A. Anand, "Three-dimensional spatial and temporal temperature imaging in gel phantoms using backscattered ultrasound" 54 : 23-31, 2007

      6 S. Sapareto, "Thermal dose determination in cancer therapy" 10 : 787-800, 1984

      7 K. Maeda, "The safety use of diagnostic ultrasound in obstetrics and gynecology" 6 : 313-317, 2012

      8 J. Jakobsen, "The safety of ultrasound contrast agents" 15 : 941-945, 2005

      9 K. Meada, "The limitation of the ultrasound intensity for diagnostic devices in the Japanese industrial standards" 33 : 241-244, 1986

      10 J. Lehmann, "The biophysical basis of biologic ultrasonic reactions with special reference to ultrasonic Therapy" 34 : 139-151, 1953

      11 D. Ellis, "The Monopole-source solution for estimating tissue temperature increases for focused ultrasound fields" 43 : 88-97, 1996

      12 J. Wu, "Temperature elevation generated by a focused gaussian beam of ultrasound" 16 : 489-498, 1990

      13 J. Quistgaard, "Signal acquisition and processing in medical diagnostic ultrasound" 14 : 67-74, 1997

      14 H. Elizabeth, "Safety limitations of MR-HIFU treatment near interfaces: a phantom validation" 13 : 168-175, 2012

      15 W. Fry, "Production of focal destructive lesions in the central nervous system with ultrasound" 11 : 471-478, 1954

      16 K. Hynynen, "Potential adverse effects of high-intensity focused ultrasound exposure on blood vessels in vivo" 22 : 193-201, 1996

      17 D. Miller, "Overview of therapeutic ultrasound applications and safety considerations" 31 : 623-634, 2012

      18 R. Seip R, "Noninvasive estimation of tissue temperature response to heating fields using diagnostic ultrasound" 42 : 828-839, 1995

      19 D. Gebauer, "Low-intensity pulsed ultrasound: effects on nonunions" 31 : 1391-1402, 2005

      20 J. Kennedy, "High intensity focused ultrasound: surgery of the future?" 76 : 590-599, 2003

      21 W. Nyborg, "Heat generation by ultrasound in a relaxing medium" 70 : 310-312, 1981

      22 C. Lafon, "Gel phantom for use in high-intensity focused ultrasound dosimetry" 31 : 1383-1389, 2005

      23 "GENU Carrageenan book" cpkelco

      24 L. Kinsler, "Fundamentals of Acoustics" John Wiley & Sons 526-, 2000

      25 N. Miller, "Fundamental limitations of noninvasive temperature imaging by means of ultrasound echo strain estimation" 28 : 1319-1333, 2002

      26 "FAO Agar and Carrageenan Manual"

      27 T. Mast, "Empirical relationships between acoustic parameters in human soft tissues" 1 : 37-42, 2000

      28 D. Miller, "Diagnostic ultrasound-induced membrane damage in phagocytic cells loaded with contrast agent and its relation to doppler-mode images" 49 : 1094-1102, 2002

      29 T. Samulski, "Clinical experience with a multielement ultrasonic hyperthermia system: analysis of treatment temperatures" 6 : 909-922, 1990

      30 F. Kremkau, "Cancer therapy with ultrasound: A historical review" 7 : 287-300, 1979

      31 J. Browne, "Assessment of the acoustic properties of common tissuemimicking test phantoms" 29 : 1053-1060, 2003

      32 J. Kim, "Acoustic characteristics of a tissue mimicking phantom for visualization of thermal distribution" 51 : 07GB10-, 2012

      33 M. Choi, "A tissue mimicking polyacrylamide hydrogel phantom for visualizing thermal lesions generated by high intensity focused ultrasound" 39 : 439-448, 2013

      34 H. Klingler, "A novel approach to energy ablative therapy of small renal tumours: laparoscopic high-intensity focused ultrasound" 53 : 810-816, 2008

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      2001-07-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      1999-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      2016 0.23 0.23 0.22
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