사람태아골모세포에 대한 GBM의 골형성 유도에 관한 효과 = Effects of GBM(Gelatinized Bone Matrix) on Bone Formation in Human Fetal Osteoblasts

다국어 초록 (Multilingual Abstract)

The purpose of the present study was to investigate the effects of GBM on the activity, differentiation and alkaline phosphatase(ALP) synthesis of hFOB1s. To examine the cellular activity, hFOB1s were cultured with DMEM/F-12 1:1 Mixture and 100 ㎍, 2 mg, 5 mg, 10 mg of GBM for 2 days and 4 days. To compare the ALP synthesis, hFOB1s were cultured with DMEM/F-12 1:1 Mixture and 100 ㎍, 2 mg, 5 mg, 10 mg, 20 mg of GBM for 3days. The cellular activity of hFOB1s treated with 100 ㎍ of GBM was increased at 2 and 4-day(p＞0.05) to control. The activity of ALP in hFOB1s treated with 100 ㎍ GBM was significantly increased at 3 day(p＜0.05).
This study indicated that 100 ㎍ of GBM has an inductive effect on bone formation in vitro increasing with cell proliferation, ALP activity.

목차 (Table of Contents)

• Ⅰ. 서론
• Ⅱ. 연구 재료 및 방법
• Ⅲ. 결과
• Ⅳ. 총괄 및 고찰
• Ⅴ. 결론
• 참고문헌
• ABSTRACT