吸入 細胞檢査의 診斷的 意義 및 評價 : 여러 人體 藏器에서 經驗한 1005例를 中心으로 An Analysis of 1,005 Cases from Various Human Organs = Aspiration Biopsy Cytology : Its Diagnostic Significance and Evaluation

국문 초록 (Abstract)

吸入 細胞檢査(Aspiration Biopsy Cutology, ABC)는 目的 病巢에서 細針을 揷入하여 吸入한 微細組織切片을 細胞學的 檢査法으로 判讀 診斷하는 檢査法이다. 매우 簡單하고 迅速한데 比해 正確性과 安定性이 높고, 뿐만 아니라 患者에게 心的 肉體的 負擔과 合倂症이 적고 低廉한 費用으로 行할 수 있어 最近 우리나라에서도 漸次的으로 利用度가 높아지고 있다. 短點이라면 僞陰性 結果가 不可避하다는 것이다. 이를 最少限으로 줄이기 爲해서는 技法의 熟練과 判讀하는 病理專門醫들의 豊富한 經驗이 必要하다.
本 硏究 結果 診斷의 正確度는 90%이었으며 將次 向上될 것으로 期待된다.

다국어 초록 (Multilingual Abstract)

An analysis of 1,005 cases of Aspiration Biopsy Cytology (ABC) performed at Seoul Paik Hospital from February 1984 to September 1986 was reviewed.
The following results were obtained.
1.Number of the test performed is 173 in 1984, 387 in 1985 and 445 in 1986, respectively.
2.Aspiration Biopsy Cytology was most frequently applied to lymph node with incidence of 394 (39%), breast 296 (29%), thyroid 132 (13%), deep organs 86 (9%) and others 97 cases (10%).
3.The most frequently made Aspiration Biopsy Cytology diagnosis was mammary dysplasia of 144 cases followed by reactive hyperplasia of lymph node 118, lymph node malignancy 73 and adenomatous goiter 50. Malignancy is the most frequent diagnosis made in this study, occupying over 23% of the test performed. The result is indirectly suggested that the Aspiration Biopsy Cytology is an important tool for detection of the malignant lesion.
4.Histological diagnosis was made in 116 cases and diagnostic accuracy of Aspiration Biopsy Cytology ranged from 75.1(81.1)% to 94.3(98.0)%. The mean accuracy is 89.3(91.5)%.
5.There were 3(2.6%) cases of false positive and 9(7.8%) false negative reports of Aspiration Biopsy Cytology. The former consists of 1 case of granuloma and 2 cases of osteomyelitis reported as highly suspicious Aspiration Biopsy Cytology impresssion. The fault was made due to atypical epitheloid cells and active osteoblasts. The false nagative consists of 3 cases of sampling error, 4 cases of misinterpretation and 2 cases of diagnostic difficulty; one well differenciated follicular carcinoma impressed as adenomatous goiter in Aspiration Biopsy Cytology and the other well differenciated duct adenocarcinoma of breast with impression of papilloma in Aspiration Biopsy Cytology.
6.Diagnosis of non-neoplastic lesion is also significantly effective. For example; diagnosis of tuberculosis is more effectively made with combination study of Aspiration Biopsy Cytology and acid fast (rhodamine) stain.
7.Aspiration Biopsy Cytology is an extention of morphologic diagnosis within both diagnostic cytology and histopathology. It is quite valuable method previously underused and wider use of this established and simple procedure is encouraged.

목차 (Table of Contents)

• Ⅰ.서론
• Ⅱ.대상 및 방법
• A.대상
• B.방법
• Ⅲ.성적
• Ⅳ.고안
• 1.ABC의 종류
• 2.염색
• 3.ABC의 이점(Advantage)
• 4.결점(Disadvantage)
• 5.본 연구 결과의 분석 및 평가
• Ⅴ.결론