(Helicobacter pylori 감염)과 연관된 (Henoch-Schonlein purpura) 4례 = 4 Cases of Henoch-Schonlein purpura associated with Helicobacter pylori infection

다국어 초록 (Multilingual Abstract)

Henoch-Schonlein purpura(HSP), known as hyperergic leukocytoclastic vasculitis, is characterized by various associated signs and symptoms primarily involving the skin, the gastrointestinal tract, the kidneys, the joints, and the nervous system.
The hallmark of the disease is the rash, beginning as pinkish maculopapules. Arthritis is usually localized to the knees and ankles and appears to be concomitant with edema. Edema and damage to the vasculature of the gastrointestinal tract may also lead to intermittent abdominal pain that is often colicky in nature. Renal involvement occurs in 25-50% of children
The pathogenesis of HSP remains poorly understood, but it is postulated that an unknown antigenic stimulus causes elevation of circulating IgA and that complement activation leads to necrotizing vasculitis
It typically occurs after infection of the upper respiratory tract. However, a wide variety of different conditions may also be involved. Recent reports have described an association between Helicobacter pylori(HP) infection of the gastric mucosa and HSP, suggesting a possible pathogenetic relationship.
We report patients with HSP who presented with HP infection tests are positive and discuss about that.