발효 흑대추 추출물의 항산화 효과

다국어 초록 (Multilingual Abstract)

This study was conducted to analyze the antioxidant activities of fermented black jujube and to compare these with those of dried jujube, for the development of functional materials. The antioxidative activities of dried jujube and fermented black jujube extracts were analyzed by electron-donating ability (EDA) using 1,1-diphenyl-2-picryl hydrazyl (DPPH), superoxide-dismutase-(SOD)-like activity by pyrogallol, nitrite-scavenging ability, and xanthin oxidase. The yield of the fermented black jujube extracts was higher than that of the dried jujube extracts, and that of the ethanol extracts was higher than that of the hot-water extracts. The total phenol contents of the hot-water extracts from fermented black jujube were higher. The EDA values of the hot-water and ethanol extracts from fermented black jujube and dried jujube increased with an increase in extract concentration, and were about 85% in a 1000 ㎍/mL extract concentration. The SOD-like activity increased with an increase in extract concentration. The SOD-like activity of the hot-water extract from fermented black jujube was higher than that of the other extracts. The nitrite-scavenging ability at pH 1.2 of the hot-water extracts from dried jujube was higher than that of the other extracts. The xanthine oxidase inhibitory activities of the hot-water and ethanol extracts from fermented black jujube were higher than those of the other extracts, and increased along with the concentrations of the extracts.

참고문헌 (Reference)

1 정명훈, "초고압 추출 공정을 통한 고로쇠 목부 추출물의 항암활성 증진" 한국약용작물학회 18 (18): 157-167, 2010

2 예은주, "장뇌삼 및 장뇌삼엽차의 생리활성평가" 한국식생활문화학회 25 (25): 350-356, 2010

3 이승욱, "울릉도산 산채류 추출물의 총 폴리페놀 함량 및 항산화 활성" 한국식품과학회 37 (37): 233-240, 2005

4 김승섭, "생더덕과 발효더덕의 유용생리활성 비교" 한국약용작물학회 17 (17): 280-285, 2009

5 송희순, "빨간함초의 지질과산화 및 라디칼 형성에 대한 항산화 활성" 한국식품영양학회 20 (20): 150-157, 2007

6 박영서, "복분자의 유산발효와 생리활성 평가" 한국응용생명화학회 46 (46): 367-375, 2003

7 우관식, "반응표면분석에 의한 건대추의 추출조건 최적화" 한국식품영양과학회 38 (38): 244-251, 2009

8 주광지, "대추 메탄올 추출물의 페놀성 화합물 함량과 항산화 효능" 한국식품영양과학회 34 (34): 750-754, 2005

9 이승은, "느릅나무와 시무나무의 항산화 활성" 한국약용작물학회 12 (12): 321-327, 2004

10 박병학, "가열처리한 대추 농축액의 물리화학적 특성" 동아시아식생활학회 18 (18): 190-197, 2008

11 Stirpe F, "The regulation of rat liver xanthine oxidase" 244 : 3855-3861, 1969

12 Stirpe F, "The regulation of rat liver xanthine oxidase" 244 : 3855-3861, 1969

13 Kang YH, "The nitrite scavenging and electron donating ability of phenolic compounds" 28 : 232-239, 1996

14 Yagi A, "Studies on the constituents of Zizyphi frutus" 26 : 1798-1802, 1978

15 Choi KS, "Studies on the chemical compositions and antitumor activities of jujube tea products" 22 : 23-29, 2003

16 Okamura N, "Studies of dammarane-type saponin of Zizyphus fructus" 29 : 675-683, 1981

17 Park YH, "Screening of inhibitory effect of edible mushrooms on tyrosinase and isolation of active component" 12 : 195-199, 1997

18 Marklund S, "Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase" 47 : 469-474, 1974

19 Kato H, "Inhibitory of nitrosamine formation by nondilyzable melanoidins" 51 : 1333-1338, 1987

20 Cyong JC, "Identification of guanosine 3':5'-mono phosphate in the fruit of Zizyphus jujuba" 21 : 1871-1874, 1982

21 Kawaguchi K, "Hesperidin as an inhibito of lipases from porcine pancreas and pseudomonas" 61 : 102-104, 1997

22 Biesalski HK, "Free radical theory of aging" 5 : 5-10, 2002

23 Cha JY, "Effects of hesperetin and naringenin on lipid concentration in oratic acid treated mice" 9 : 389-394, 1999

24 Na HS, "Effect of jujube methanol extract on the hepatotoxicity in CCl4-treated rats" 25 : 839-845, 1996

25 Lee YG, "Effect of jujube methanol extract on benzo(a)pyrene induced hepatotoxicity" 24 : 127-132, 1995

26 Bal JS, "Development physiology of ber (Zizyphus mauritina) var. urman. Ⅳ. Change in amino acids and sugar(sucrose, glucose and fructose) at different stages of fruit ripening" 33 : 3335-3337, 1979

27 Storch I, "Detergent-amplified chemiluminescence of Iucigenin for determination of superoxide amino production by NADPH oxidase and xanthine oxidase" 169 : 262-267, 1988

28 Singleton VL, "Colorimetry of total phenolics with phosphomolybdic-phosphotungstic acid reagents" 16 : 144-158, 1965

29 Park YB, "Characteristics of nitrite scavenger derived from seeds of Cassia tara L" 27 : 124-128, 1995

30 Shin SR, "Changes in the components of dried jujube fruit by drying methods" 6 : 61-65, 1999

31 Choi KS, "Changes in physiological and chemical characteristics of jujube fruits var. bokjo during maturity and postharvest ripening(in Korean)" 9 : 47-53, 1990

32 Lee KD, "Antioxidative effectiveness of water extract and ether in wormwood (Artemisiamontana pampan)" 21 : 17-22, 1992

33 Blois ML, "Antioxidant determination by the use of a stable free radical" 181 : 1199-1224, 1958

34 Kim YJ, "Antioxidant and anticancer effect of dried jujube sarcocarp, seed and leaf extracted with different solvents" Daegu Haanny University 2010

35 Zryaev R, "Alkaloids of Ziziphus jujuba structure of yuziphine and yuzirine" 2 : 239-243, 1977

36 Yu BP, "Aging and oxidative stress: Modulation by dietary restriction" 21 : 651-668, 1996

37 Harman D, "A theory based on free radical and radiation chemistry" 11 : 298-307, 1956

38 김현구, "1. 에탄올 농도에 따른 머루(Wild Grape, Vitis coignetiae) 추출물의 폴리페놀 함량 및 항산화 활성" 한국식품영양과학회 36 (36): 1491-1496, 2007