頭蓋骨에 發生한 原發性 Ewing’s Sarcoma : 症例報告 Report of A Case = Primary Ewing’s Sarcoma of the Skull

다국어 초록 (Multilingual Abstract)

Ewing's sarcoma is a malignant tumor of the bone which is common in the long bone and pelvic bone but is very rare in the skull.
The authors have had a primary Ewing's sarcoma of the skull on a 7 years old girl.
7 years old girl happened to notice the small elastic hard mass on the right parietal region since about 3 months prior to admission which grew gradually without any pain or other symptoms.
On admission, physical examination revealed T:37.5'C, P:94/min and B.P: 100/80mmHg, and there was small egg sized mass on the right parietal region. Except it, there was no abnormal neurological and physical findings.
The laboratory data revealed WBC:8, 800(Neurto.; 68%, Lympho.; 27% and Eosino.; 5%), hemoglobin: 9. 0Gm% blood Alkaline Phosphatase: 9. 0 Bodansky Units, and urinalysis and stool examinations were within normal limits.
X-ray findings: All long bone and pelvic bone check revealed no abnormalities.
Skull showed soft tissue swelling on the right parietal region and sun-burst appearance of the skull at the area.
Operation: The patient underwent second stage surgery on the tumor(First time biopsy and second time total excision). Tissue pathology revealed decalcified osteoid bone which shows osteolytic changes, which has evidence of infiltration of indistinct nucleoli and cytoplasmic border of anaplastic cells having with round and oval shaped of cell all throughout at around blood vessels. Also tumor mass contains abundant vascularity and associated with fibrous septal formation.
The patient was discharged from hospital 10 days after second surgery but did not receive radiation therapy and was reported she succumbed 3 months after the second surgery.