파킨슨병 환자의 유형별 외적 신호의 제공에 따른 협응 운동 수행력의 차이 연구 = Effects of External Cues on Performance of Simultaneous Bimanual Movements in Two Distinctive Characteristics of Parkinson`s Disease

다국어 초록 (Multilingual Abstract)

It has been suggested that external cues induce a marked improvement in motor performance by reducing movement disorders due to Parkinson`s disease (PD). The purpose of this study was to investigate the influence of external cues on the performance of upper-limb bimanual coordination movements using 10 PD patients in advanced stages and 10 early stages of untreated PD patients, and 10 age-matched normal controls. The results demonstrated that normal controls and de novo PD patients exhibited an improved synchronized coordination during the anti-phase mode, while there was not much changes in relative phase for advanced PD patients in the presence of external cues. This fact indicates that in case of advanced PD patients who have taken anti-Parkinson medicine for more than 5 years their performance was not greatly influenced by external cues when the task complexity or difficulty is elevated such as unsymmetrical anti-phase movements. Enhancement in movement speed and amplitude control was observed in both PD groups. However, movement harmonicity was shown improved only in advanced PD group. The results of this study might help understanding the underlying mechanism for the positive effects of external cues on the patient`s capability and could be utilized as a basic index for the diagnosis and treatment for PD patients from the practical standpoint.

참고문헌 (Reference)

1 이효경, "한 손의 힘 조건 변화에 따른 양손 협응 형태" 40 (40): 1001-1009, 2001

2 이대희, "파킨슨병이란 무엇인가?" 범문사 2005

3 송용관, "연습시간의 배분에 따른 양팔협응 패턴의 안정성과 학습의 효과" 한국체육학회 46 (46): 191-203, 2007

4 윤기운, "양손 협응동작의 제어 기제" 6 (6): 1-26, 1995

5 권승민, "골프 피치 샷 과제 수행 시 주의초점 피드백에 따른 학습 효과 및 협응구조" 한국스포츠심리학회 18 (18): 13-30, 2007

6 Freeman, J. S, "The influence of external timing cues upon the rhythm of voluntary movements in Parkinson’'s disease" 56 : 1078-1084, 1993

7 Bagley, S, "The effect of visual cues on the gait of independently mobile Parkinson's disease patients" 77 : 415-420, 1991

8 Zanone, P. G, "The coordination dynamics of learning: Theoretical structure and experimental agenda. In Interlimb coordination: Neural, dynamical, and cognitive constraints" Academic Press 461-490, 1994

9 Castiello, U, "The bilateral reach to grasp movement" 56 : 43-57, 1993

10 Rochester, L, "The attentional cost of external rhythmical cues and their impact on gait in Parkinson's disease:effect of cue modality and task complexity" 114 (114): 1243-1248, 2007

11 Teasdale, N, "Temporal movement control in patients with Parkinson's disease" 53 : 862-868, 1990

12 Morris, M. E, "Stride length regulation in Parkinson’s disease:Normalization strategies and underlying mechanisms" 119 : 551-568, 1996

13 Lee, T. D, "Relative Phase Alterations During Bimanual Skill Acquisition" 27 (27): 263-274, 1995

14 Khudados, E, "Proprioceptive regulation of voluntary ankle movements,demonstrated using muscle vibration,is impaired by Parkinson's disease" 67 : 504-510, 1999

15 Rickards, C, "Proprioceptive control of wrist movements in Parkinson’s disease:Reduced muscle vibration-induced errors" 120 : 977-990, 1997

16 Carson, R. G, "Phase transitions and critical fluctuations in rhythmic coordination of ipsilateral hand and foot" 27 : 211-224, 1995

17 Kelso,J.A.S, "Phase transitions and critical behavior in human bimanual coordination.American Journal of Physiology:Regulatory" 15 : 1000-1004, 1984

18 Alexander, G.E, "Parallel organization of functionally segregated circuits linking basal ganglia and cortex" 9 : 357-381, 1986

19 Guiard,Y, "On Fitts’s and Hooke’s laws:simple harmonic movement in upper-limb cyclical aiming" 82 : 139-59, 1993

20 Rand, M. K, "Movement accuracy constraints in Parkinson's disease patients" 38 : 203-212, 2000

21 Chan, J. L, "Left-handed mirror writing following right anterior cerebral artery infarction:evidence for nonmirror transformation of motor programs by right supplementary motor area" 38 : 59-63, 1988

22 Swinnen,S.P, "Intermanual coordination:from behavioural principles to neural-network interactions" 3 : 348-359, 2002

23 Swinnen, H. Heuer, "Interlimb coordination: Neural, dynamical, and cognitive constraints" Academic Press 461-490,

24 Luria,A.R, "Human brain and psychological processes" Harper & Row 1996

25 Zanone, P. G, "Evolution of behavioral attractors with learning:Nonequilibrium phase transitions" 18 : 403-421, 1992

26 Swinnen, S. P, "Egocentric and allocentric constraints in the expression of patterns of interlimb coordination" 9 (9): 348-377, 1997

27 Kelso, J. A. S, "Cooperative phenomena in biological motion. In Complex systems: Operational approaches in neurobiology. Physical systems, and computers" Springer-Verlag 124-149, 1985

28 Fagard,J, "Bimanual stereotypes:bimanual coordination in children as a function of movements and relative velocity" 19 : 355-366, 1987

29 Li, Y, "Bimanual coordination:constraints imposed by the relative timing of homologous muscle activation" 156 (156): 27-38, 2003

30 Ponsen, M. M, "Bimanual coordination dysfunction in early,untreated Parkinson's disease" 12 (12): 246-252, 2006

31 Almeida, Q. J, "Bimanual coordination deficits with Parkinson's disease: the influence of movement speed and external cueing" 17 (17): 30-37, 2002

32 Serrien, D. J, "Bimanual coordination and limb-specific parameterization in patients with Parkinson's disease" 38 : 1714-1722, 2000

33 Georgiou, N, "An evaluation of the role of internal cues in the pathogenesis of parkinsonian hypokinesia" 116 : 1575-1587, 1993

34 Swinnen, S. P, "Acquiring bimanual skills:contrasting forms of information feedback for interlimb decoupling" 19 (19): 1328-1344, 1993