한국인 집단의 유전학적 연구 - 10. 한국인 미토콘드리아 DNA 의 유전적 다형 - = Genetic Studies on the Korean Population - 10. Genetic Polymorphisms of Korean Mitochondria DNA -

다국어 초록 (Multilingual Abstract)

In order to study RFLPs (Restriction Fragment Length Polymorphisms) of mitochondrial DNA (mtDNA) in Korean population, the authors obtained the mtDNA from 60 placentae and digested with 6 kinds of restriction endonucleases (Hea II, Hind III, Bam HI, Eco Ri, Pst I and Hpa I) recognizing hexanucleotide. And RFLPs for each mtDNA were analyzed. All of the mtDNA obtained from 60 placenate were classified into seven mtDNA types (type 1, 6, 8, 13, 27 and 7*) by combining the results obtained from the digestion of mtDNA with 6 kinds of restriction endonucleases. However, the type 7*(4-1-1-1-1) which was not reported in other racial populations was referred to as a new type. In the calculation of nucleotide diversity the authors obtained the mean value of δ=0.00688±0.00296. As the results mentioned above it is concluded that Korean population is belong to Mongoloid racial population in relation to RFLPs of mtDNA comparing with oriental population which is consisted of many races including Korean. However, for the more valuable results of mtDNA RFLPs in Korean population, the authors believe that the more extensive samples and various informative restriction endonucleases are required.