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The protective roles of metallothionein(MT) exogeneously adiministered have been examined in the liver and kidney of cadmium(Cd) treated mouse, In Cd treated mouse, cellular damages such as nuclear pyknosis and necrosis were observed, Increased interc...
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RISS 인기검색어
카드뮴 독성에 대한 Metallothionein의 보호 작용 = Effects of Metallothionein of Toxicity of Cadmium in Mouse
한글로보기https://www.riss.kr/link?id=A75060742
- 저자
- 발행기관
- 학술지명
- 권호사항
-
발행연도
2005
-
작성언어
Korean
- 주제어
-
KDC
405.000
-
자료형태
학술저널
-
수록면
33-42(10쪽)
- 제공처
- 소장기관
-
0
상세조회 -
0
다운로드
부가정보
다국어 초록 (Multilingual Abstract)
The protective roles of metallothionein(MT) exogeneously adiministered have been examined in the liver and kidney of cadmium(Cd) treated mouse, In Cd treated mouse, cellular damages such as nuclear pyknosis and necrosis were observed, Increased intercellular spaces and obscure liver lobules were often observed. The extent of damages of liver cells in Cd-MT treated group decreased compared with Cd treated group. And also, MT reactivity of this group was prominent in nuclei and cytoplasm. The enzyme activities of ALT and AST showed less alterations in CchMT treated group. In the case of kidney, protective effects of MT against Cd toxicity were comparatively not clear, In conclusion, these experimental results suggest that metallothionein reduces cellular damages resulted from cadmium in the liver of mouse.
The protective roles of metallothionein(MT) exogeneously adiministered have been examined in the liver and kidney of cadmium(Cd) treated mouse, In Cd treated mouse, cellular damages such as nuclear pyknosis and necrosis were observed, Increased intercellular spaces and obscure liver lobules were often observed. The extent of damages of liver cells in Cd-MT treated group decreased compared with Cd treated group. And also, MT reactivity of this group was prominent in nuclei and cytoplasm. The enzyme activities of ALT and AST showed less alterations in CchMT treated group. In the case of kidney, protective effects of MT against Cd toxicity were comparatively not clear, In conclusion, these experimental results suggest that metallothionein reduces cellular damages resulted from cadmium in the liver of mouse.
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