뇌졸중 후 발생한 괴잉성욕에 대한 Cimetidine의 치료효과 : 증례보고 = Cimetidine Treatment of Hypersexuality Associated with Stroke

다국어 초록 (Multilingual Abstract)

Most studies have agreed that there is a considerable decline in sexual activity following stroke. but the hypersexuality after stroke as a relatively isolated behavioral abnormality has been less frequently reported Hypersexuality has no proven treatment, although reports have described reductions in hypersexual behavior did not response to three medications were not uncommonly observed in clinical practice A 65-year-old right-handed male presented with acute left hemipararesis. His MRI showed a right middle cerebral artery infarct involving the temporal, parietal regions and the basal ganglia. Four weeks after stroke he showed abnormal behavior, such as incessantly holding and hugging the nursing staff without assent, but no increased orality or change in eating habits But several weeks after taking cimetidine. a histamine H₂-receptor antagonist. his sexual behavior showed a marked improvement This case demonstrates that cimetidine as a non-hormonal anti-androgenic effect decreased libido and hypersexual behavior without serious side effects in patients with cognitive decline after stroke Further studies that obviously define the response and long-term side effects of cimetidine are needed to confirm our observations.