The Clinical Impacts of Apparent Embolic Event and the Predictors of In-Hospital Mortality in Patients with Infective Endocarditis

다국어 초록 (Multilingual Abstract)

Embolic event is a common and important complication of infective endocarditis (IE). Theobjective of this study was to investigate the clinical impacts of embolic event in patientswith IE and the predictors of in-hospital mortality. Data was collected in Pusan NationalUniversity Hospital and Pusan National University Yangsan Hospital between January 2009and December 2010. One hundred ten patients were included. Embolic events occur in 39of 110 patients (35.5%). Brain (n = 18, 38.5%) was the main site of embolic infarction.

Patients with embolism showed higher in-hospital mortality (46.2% vs. 8.5%, respectively,P = 0.03), more frequent ICU admission (53.8% vs. 35.2%, respectively, P = 0.045) andmore accompanying other cardiac complication (43.6% vs. 21.1%, respectively, P = 0.017).

The in-hospital mortality rate was 18.2%. On the logistic regression analysis of the predictorsfor in-hospital mortality, age (RR, 1.079; 95% CI, 1.036-1.123, P = 0.001), embolic event(RR, 3.510; 95% CI, 1.271-9.69, P = 0.015) and staphylococcal infection (RR, 5.098;95% CI, 1.308-18.508, P = 0.023) were independently associated with in-hospital mortality.

Embolic events in IE are associated with poor in-hospital outcome; and these data aboutembolic events and the predictors of in-hospital mortality may improve the managementof this disease in hospitals.

참고문헌 (Reference)

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