당질의 종류가 정상인과 당뇨병환자의 혈청 Glucose 및 혈청 Fructose에 미치는 영향

다국어 초록 (Multilingual Abstract)

Fructose has been claimed to offer advantage for diabetic individuals since it produces less hyperglycemia. However, previous studies have focused only on serum glucose responses, and thus do not address to the effect on serum fructose.
This study was performed to investigate the effect of various simple sugars on serum glucose and fructose in normal and diabetic subjects.
Subjects were given either 75g glucose, 75g fructose, 75g sucrose or 112.5g fructose in fasting state and their serum glucose and fructose levels were measured at 0,1,2 and 3 hours.
The results were as following :
1) Fructose ingestion resulted in significantly lower serum glucose than ingestion of either sucrose or glucose both in normal and diabetic subjects.
2) Increment in serum fructose was highest after ingestion of fructose compared to ingestion of sucrose or glucose both in normal and diabetic subjects.
3) In normal subjects, serum fructose level increased as the dose of fructose in creased.
4) In diabetic subjects, serum fructose level remained at high level and became significantly higher than normal subjects after 3 hours.
5) Fructose, sucrose and glucose were compared for its possible biohazard (△ glucose plus △ fructose x 7.5) and sucrose gave highest numbers in diabetic subjects.
There result raise possibility that ingestion of fructose and sucrose can produce undesirable effects in diabetics.

목차 (Table of Contents)

• 목차
• I. 서론 = 1
• II. 대상 및 실험방법 = 4
• A. 대상 = 4
• B. 실험방법 = 7
• 1. 실험기구 및 시약 = 7
• 2. 당부하 검사 = 8
• 3. 혈청 glucose 측정 = 8
• 4. 혈청 fructose 측정 = 10
• 5. Data 처리 = 10
• III. 실험결과 = 11
• A. 혈청 glucose = 11
• B. 혈청 fructose = 12
• IV. 고찰 = 22
• V. 결론 = 34
• VI. 참고문헌 = 36
• 영문초록(Abstract)