돼지고기를 단백질 급원으로 한 식이가 쥐의 체내 카드뮴 대사에 미치는 영향에 대한 연구 = Effect of Pork as a Protein Source on Cadmium Toxicity in Rats

다국어 초록 (Multilingual Abstract)

This study was performed to investigate the effect of feeding pork in the place of casein on cadmium toxicity in rats. Thirty six male rats of Sprague-Dawley weighing 225.2?9.3g were randomly blocked into six groups according to body weights. Three levels of cadmium in drinking water(0, 25 and 50 ppm) had been fed for 5 weeks. Pork replaced dietary casein as a protein source. Weight gains in either cadmium-added or pork-fed group tended to be lower than those of the control group(Cd 0 ppm and casein). The cadmium addition and pork feedings affect significantly feed efficiency according to factor analysis results. Hematocrit was decreased with cadmium intake(p$lt;0.05). Cadmium accumulation in liver showed a tendency to diminish in the pork-fed group among the cadmium-exposed groups. Hepatic enzyme activity of glutatione peroxidase and superoxide dismutase showed no significant differences among the treatments. Urinary and fecal cadmium excretions increased with pork feeding. The results indicate that pork feeding as protein source in diet may alleviate the cadmium toxicity in rats.