Mixed Infection of Mycobacterium abscessus subsp. abscessus and Mycobacterium tuberculosis in the Lung

다국어 초록 (Multilingual Abstract)

A mixed infection of Mycobacterium abscessus subsp. abscessus (Mab) and Mycobacterium tuberculosis (MTB) in the lung is an unusual clinical manifestation and has not yet been reported. A 61-year-old woman had been treated for Mab lung disease and concomitant pneumonia, and was diagnosed with pulmonary tuberculosis (PTB). Despite both anti-PTB and anti-Mab therapy, her entire left lung was destroyed and collapsed. She underwent left pneumonectomy and received medical therapy. We were able to successfully treat her mixed infection by pneumonectomy followed by inhaled amikacin therapy. To the best of our knowledge, thus far, this is the first description of a mixed Mab and MTB lung infection.

참고문헌 (Reference)

1 Huang HC, "Unusual mixed infection of thoracic empyema caused by Mycobacteria tuberculosis, nontuberculosis mycobacteria and Nocardia asteroides in a woman with systemic lupus erythematosus" 54 : e25-e28, 2007

2 Kang HK, "Treatment outcomes of adjuvant resectional surgery for nontuberculous mycobacterial lung disease" 15 : 76-, 2015

3 Madansein R, "Surgical treatment of complications of pulmonary tuberculosis, including drug-resistant tuberculosis" 32 : 61-67, 2015

4 Hwang SM, "Simultaneous detection of Mycobacterium tuberculosis complex and nontuberculous mycobacteria in respiratory specimens" 93 : 642-646, 2013

5 McShane PJ, "Pulmonary disease due to nontuberculous mycobacteria : current state and new insights" 148 : 1517-1527, 2015

6 Olivier KN, "Inhaled amikacin for treatment of refractory pulmonary nontuberculous mycobacterial disease" 11 : 30-35, 2014

7 Chen TC, "Fluoroquinolones are associated with delayed treatment and resistance in tuberculosis: a systematic review and meta-analysis" 15 : e211-e216, 2011

8 Griffith DE, "An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases" 175 : 367-416, 2007