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      우리나라 정상성인에서 Stacked 청성뇌간반응과 Cochlear Hydrops Analysis Masking Procedure의 성별 및 연령별 차이분석 = An Analysis of Difference in Age and Gender of Stacked Auditory Brainstem Response and Cochlear Hydrops Analysis Masking Procedure in Korean Normal Adults

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      https://www.riss.kr/link?id=A101610070

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      Background and Objectives The stacked auditory brainstem response (SABR) was introduced to collect the low frequency information using the conventional ABR. The cochlear hydrops analysis masking procedure (CHAMP) was developed to discriminate an active Ménière's disease from others. This investigation was aimed to provide data through analyzing age and gender effects of SABR and CHAMP in Korean normal adults.
      Subjects and Method Normal hearing Korean adults (34), aged 30 to 67 participated in this study. The number of subjects for different age groups of 30s, 40s, 50s and 60s were 10, 9, 8, and 7, respectively. SABRs were tested at 60 dB nHL stimuli level of constant noise and masking clicks of high pass noise ranging at 8, 4, 2, 1 and 0.5 kHz. CHAMP responses were simply obtained for further analysis of SABR measurements. SABR amplitude, SABR interaural difference (IAD), CHAMP latency delay, and CHAMP complex amplitude ratio were analyzed and compared.
      Results The mean SABR amplitude was 683 nV showing statistical difference for age but not for gender effects. The mean SABR IAD was 6.4% with no statistical significances for both age and gender effects. The mean CHAMP latency delay and complex amplitude ratio were 4.47 ms and 0.97 with statistical significance for the effects of age but not for gender.
      Conclusion The results agreed with the foreign data in SABR and CHAMP except for the age effect of complex amplitude ratio. In order to improve clinical efficacy, investigations should be performed with more and diverse participants.
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      Background and Objectives The stacked auditory brainstem response (SABR) was introduced to collect the low frequency information using the conventional ABR. The cochlear hydrops analysis masking procedure (CHAMP) was developed to discriminate an activ...

      Background and Objectives The stacked auditory brainstem response (SABR) was introduced to collect the low frequency information using the conventional ABR. The cochlear hydrops analysis masking procedure (CHAMP) was developed to discriminate an active Ménière's disease from others. This investigation was aimed to provide data through analyzing age and gender effects of SABR and CHAMP in Korean normal adults.
      Subjects and Method Normal hearing Korean adults (34), aged 30 to 67 participated in this study. The number of subjects for different age groups of 30s, 40s, 50s and 60s were 10, 9, 8, and 7, respectively. SABRs were tested at 60 dB nHL stimuli level of constant noise and masking clicks of high pass noise ranging at 8, 4, 2, 1 and 0.5 kHz. CHAMP responses were simply obtained for further analysis of SABR measurements. SABR amplitude, SABR interaural difference (IAD), CHAMP latency delay, and CHAMP complex amplitude ratio were analyzed and compared.
      Results The mean SABR amplitude was 683 nV showing statistical difference for age but not for gender effects. The mean SABR IAD was 6.4% with no statistical significances for both age and gender effects. The mean CHAMP latency delay and complex amplitude ratio were 4.47 ms and 0.97 with statistical significance for the effects of age but not for gender.
      Conclusion The results agreed with the foreign data in SABR and CHAMP except for the age effect of complex amplitude ratio. In order to improve clinical efficacy, investigations should be performed with more and diverse participants.

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      참고문헌 (Reference)

      1 김창효, "메니에르병에서 Cochlear Hydrops Analysis Masking Procedure 검사의 진단적 의의" 대한이비인후과학회 52 (52): 956-960, 2009

      2 Watson D, "The effects of cochlear hearing loss, age and sex on the auditory brainstem response" 35 (35): 246-258, 1996

      3 Don M, "Successful detection of small acoustic tumors using the stacked derived-band auditory brainstem response amplitude" 18 (18): 682-685, 1997

      4 Yamaguch J, "Relationship between auditory brainstem response waveform and head size" 53 (53): 94-99, 1991

      5 Kim HJ, "Proposal of audiologic terminology standardization in Korea" 13 (13): 116-127, 2009

      6 Kim JS, "Measurement variables of stacked ABR: electrode montage" 2 (2): 126-134, 2006

      7 Jerger J, "Effects of age and sex on auditory brainstem response" 106 (106): 387-391, 1980

      8 Bio-logic system Corp, "Auditory Evoked Potential system (Including Electroneuronography, Stacked ABR, CHAMP & BioMap). User’s and Service Manual 590-AEPUM1" Bio-logic systems Corp 176-200, 2006

      9 Don M, "Auditory Brainstem Responses; Differential Diagnosis in Handbook of Clinical Audiology. 5th ed." Lippincott Williams & Wilkins 274-297, 2002

      10 Dehan CP, "Analysis of gender difference in the auditory brainsterm response" 100 (100): 18-24, 1990

      1 김창효, "메니에르병에서 Cochlear Hydrops Analysis Masking Procedure 검사의 진단적 의의" 대한이비인후과학회 52 (52): 956-960, 2009

      2 Watson D, "The effects of cochlear hearing loss, age and sex on the auditory brainstem response" 35 (35): 246-258, 1996

      3 Don M, "Successful detection of small acoustic tumors using the stacked derived-band auditory brainstem response amplitude" 18 (18): 682-685, 1997

      4 Yamaguch J, "Relationship between auditory brainstem response waveform and head size" 53 (53): 94-99, 1991

      5 Kim HJ, "Proposal of audiologic terminology standardization in Korea" 13 (13): 116-127, 2009

      6 Kim JS, "Measurement variables of stacked ABR: electrode montage" 2 (2): 126-134, 2006

      7 Jerger J, "Effects of age and sex on auditory brainstem response" 106 (106): 387-391, 1980

      8 Bio-logic system Corp, "Auditory Evoked Potential system (Including Electroneuronography, Stacked ABR, CHAMP & BioMap). User’s and Service Manual 590-AEPUM1" Bio-logic systems Corp 176-200, 2006

      9 Don M, "Auditory Brainstem Responses; Differential Diagnosis in Handbook of Clinical Audiology. 5th ed." Lippincott Williams & Wilkins 274-297, 2002

      10 Dehan CP, "Analysis of gender difference in the auditory brainsterm response" 100 (100): 18-24, 1990

      11 Don M, "An alternative diagnostic test for active Méniére’s disease and cochlear hydrops using high-pass noise masked responses: the complex amplitude ratio" 12 (12): 359-370, 2007

      12 Psatta DM, "Age-dependent amplitude variation of brain-stem auditory evoked potentials" 71 (71): 27-32, 1988

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