프로락틴 분비 뇌하수체 종양 절제술에 있어 내시경하 경비강 경접형동 접근법의 결과 = Results of Endoscopic Transnasal Transsphenoidal Treatment of Prolactin Secreting Pituitary Adenoma

다국어 초록 (Multilingual Abstract)

The endoscopic transnasal transsphenoidal approach is a common approach for pituitary tumor. The
objectives of our study is to report indication, efficacy, safety and endocrine result of endoscopic transnasal transsphenoidal surgery
in patients with prolactin secreting pituitary adenoma. Subjects and Method：We retrospectively reviewed the medical records of
10 patients who had received endoscopic transnasal transsphenoidal pituitary surgery of prolactin secreting pituitary adenoma.
Results：Three patients were resistant and intolerant in medical therapy. Visual symptoms were developed in 8 patients. Postoperatively,
4 patients (40%) achieved normalization of prolactin and relief of symptoms from endoscopic surgery alone. Four of
the remaining 6 patients achieved postoperative normalization of prolactin with medication. Visual symptom was improved in all
patients. One patient had postoperative diabetes insipidus. Conclusion：We believe that the endoscopic method is a safe, hardly
invasive and efficient surgical technique in prolactinoma. Medical treatment with dopamine agonist drugs is the mainstay of treatment
and endoscopic surgery will be used in cases of drug resistance, intolerance and development of acute visual symptom, we
may offer endoscopic surgery as a viable treatment option. (Korean J Otorhinolaryngol-Head Neck Surg 2008;51:429-34)

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