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      SCOPUS KCI등재 SCIE

      A focus on extracellular Ca <sup>2+</sup> entry into skeletal muscle

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      https://www.riss.kr/link?id=A107431352

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      다국어 초록 (Multilingual Abstract)

      <P>The main task of skeletal muscle is contraction and relaxation for body movement and posture maintenance. During contraction and relaxation, Ca<SUP>2+</SUP> in the cytosol has a critical role in activating and deactivating a series of contractile proteins. In skeletal muscle, the cytosolic Ca<SUP>2+</SUP> level is mainly determined by Ca<SUP>2+</SUP> movements between the cytosol and the sarcoplasmic reticulum. The importance of Ca<SUP>2+</SUP> entry from extracellular spaces to the cytosol has gained significant attention over the past decade. Store-operated Ca<SUP>2+</SUP> entry with a low amplitude and relatively slow kinetics is a main extracellular Ca<SUP>2+</SUP> entryway into skeletal muscle. Herein, recent studies on extracellular Ca<SUP>2+</SUP> entry into skeletal muscle are reviewed along with descriptions of the proteins that are related to extracellular Ca<SUP>2+</SUP> entry and their influences on skeletal muscle function and disease.</P>
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      <P>The main task of skeletal muscle is contraction and relaxation for body movement and posture maintenance. During contraction and relaxation, Ca<SUP>2+</SUP> in the cytosol has a critical role in activating and deactivating a serie...

      <P>The main task of skeletal muscle is contraction and relaxation for body movement and posture maintenance. During contraction and relaxation, Ca<SUP>2+</SUP> in the cytosol has a critical role in activating and deactivating a series of contractile proteins. In skeletal muscle, the cytosolic Ca<SUP>2+</SUP> level is mainly determined by Ca<SUP>2+</SUP> movements between the cytosol and the sarcoplasmic reticulum. The importance of Ca<SUP>2+</SUP> entry from extracellular spaces to the cytosol has gained significant attention over the past decade. Store-operated Ca<SUP>2+</SUP> entry with a low amplitude and relatively slow kinetics is a main extracellular Ca<SUP>2+</SUP> entryway into skeletal muscle. Herein, recent studies on extracellular Ca<SUP>2+</SUP> entry into skeletal muscle are reviewed along with descriptions of the proteins that are related to extracellular Ca<SUP>2+</SUP> entry and their influences on skeletal muscle function and disease.</P>

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