<P>The main task of skeletal muscle is contraction and relaxation for body movement and posture maintenance. During contraction and relaxation, Ca<SUP>2+</SUP> in the cytosol has a critical role in activating and deactivating a serie...
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https://www.riss.kr/link?id=A107431352
2017
-
SCOPUS,KCI등재,SCIE
학술저널
e378
0
상세조회0
다운로드다국어 초록 (Multilingual Abstract)
<P>The main task of skeletal muscle is contraction and relaxation for body movement and posture maintenance. During contraction and relaxation, Ca<SUP>2+</SUP> in the cytosol has a critical role in activating and deactivating a serie...
<P>The main task of skeletal muscle is contraction and relaxation for body movement and posture maintenance. During contraction and relaxation, Ca<SUP>2+</SUP> in the cytosol has a critical role in activating and deactivating a series of contractile proteins. In skeletal muscle, the cytosolic Ca<SUP>2+</SUP> level is mainly determined by Ca<SUP>2+</SUP> movements between the cytosol and the sarcoplasmic reticulum. The importance of Ca<SUP>2+</SUP> entry from extracellular spaces to the cytosol has gained significant attention over the past decade. Store-operated Ca<SUP>2+</SUP> entry with a low amplitude and relatively slow kinetics is a main extracellular Ca<SUP>2+</SUP> entryway into skeletal muscle. Herein, recent studies on extracellular Ca<SUP>2+</SUP> entry into skeletal muscle are reviewed along with descriptions of the proteins that are related to extracellular Ca<SUP>2+</SUP> entry and their influences on skeletal muscle function and disease.</P>
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