20-30대 한국인의 경피수분 손실도 연구 = The study on the transepidermal water loss of the Korean twenties and thirties

다국어 초록 (Multilingual Abstract)

Objective : Skin barrier protects skin against harmful environment. Its function includes antimicrobial barrier as well as physical barrier. But there are few studies about skin barrier function about men and women who don't have skin disease. The aim of this study is to investigate skin barrier function healthy men and women show. Method : There are many ways to measure skin barrier function, but lately transepidermal water loss is mainly used to know skin barrier function. Transepidermal water loss was measured over eight four the Korean twenties and thirties who don't have skin disease from March 14th, 2007 to March 16th 2007. We surveyed cubital fossa and cheek beside nose to measure transepidermal water loss and used vapometer. Result : After analyzed data, we concluded that cheek showed higher transepidermal water loss than cuital fossa. At cheek, the thirties had higher transepidermal water loss than the twenties. The male got higher transepidermal water loss than the female at cheek and in the average. And temperature and humidity effected on transepidermal water loss. Conclusion: In our study, it was observed that temperature and humidity effected on transepidermal water loss. In traditional korean medicine, the inbalance of cold(寒), heat(熱), dryness(燥), wetness(濕) makes many diseases and the inbalance of them induces dameum(痰飮) and the disorder of blood flow. Dameum(痰飮) and the disorder of blood flow make skin diseases made by abnormal skin barrier function in many ways. So we need to study dameum(痰飮) and the disorder of blood flow to take care of patients who have abnormal skin barrier function.

참고문헌 (Reference)

1 "피부 표면 온도의 변화와 diffusion chamber내의 온도 변화에 따른 경표피수분손실 및 피부 장벽 회복률의 변동" 34 (34): 875-885, 1996

2 "연령에 따른 경표피수분손실, 피지량 및 피부 표면 pH의 변화"

3 "아토피피부염에서 첩포시험과 경표피수분손실 측정에 의한 피부장벽기능의 연구" 20 (20): 702-709, 2000

4 "신체 각 부위에서의 경표피수분손실에 대한 연구" 34 (34): 402-406, 1996

5 "비후성 반흔/켈로이드에서 경표피수분손실의 측정을 통한 피부장벽 기능의 연구" 38 (38): 176-182, 2000

6 "대역 동의보감" 서울:법인문화사 1999

7 "素問玄機原病式" 沈陽:遼寧科學技術出版社 1999

8 "Validation of the VapoMeter, a closed unventilated chamber system to assess transepidermal water loss vs. the open chamber Tewameters" 11 : 61-69, 2005

9 "Validation of the VapoMeter, a closed unventilated chamber system to assess transepidermal water loss vs. the open chamber Tewameters" 11 : 61-69, 2005

10 "The skin barrier in healthy and diseased state" 1758 (1758): 2080-2095, 2006

11 "The correlation between transepidermal water loss and percutaneous absorption: an overview" 103 : 291-299, 2005

12 "Tapte Stripping과 Sodium Lauryl Sulfate에 의한 피부 장벽기능의 손상 및 회복에 관한 연구" 38 (38): 183-190, 2000

13 "Tape Stripping에 의한 각질층 제거 정도에 따른 피부장벽기능의 변화" 13 (13): 919-925, 2005

14 "Stress-induced changes in skin barrier function in healthy women" 117 (117): 309-317, 2001

15 "Stratum corneum structure and function corelates with phenotype in psoriasis" 107 : 558-564, 1996

16 "Stratum corneum lipid abnormalities on atopic dermatitis" 219-23,

17 "Role of ceramaide 1 in the molecular organization of the stratum corneum lipis" 39 : 186-196, 1998

18 "Interrelationship between water barrier and reservoir function in pathologic stratum corneum" 642-5,

19 "High-expression of sphingomyelin deacylase is an important determinant of ceramide deficiency leading to barrier disruption in atopice dermatitis" 115 : 406-413, 2002

20 "Decreased levels of ceramides in stratum corneum of atopic dermatitis an etiological factor in atopic dermatitis" 523-6, jinvestdermatol1991

21 "Correlation of clinical features and skin barrier function in adolescent and adult patients with atopic dermatitis" 45 (45): 698-701, 2006.06

22 "Comparative evaporimetry in man" 11 : 205-208, 2005

23 "An update of the defensive barrier function of skin" 47 (47): 293-306, 2006

24 "Abnormality in water barrier function on psoriasis role of ceramide function" 452-6,

25 "A portable device using a closed chamber system for measuring transepidermal water loss: comparison with the conventional method" 8 : 712-, 2002

26 "A closed unventilated chamber for the measurement of transepisermal water loss" 9 : 85-89, 2003