중복 감염된 표재성 피부 진균증에 관한 면역학적 연구 = 중복 감염된 표재성 피부 진균증에 관한 면역학적 연구

다국어 초록 (Multilingual Abstract)

The concurrent superficial fungal infection is frequently caused by autoinoculation from one part to another, especially in tinea pedis which is often the infectious source of tinea cruris and tinea manus. The difference in cell mediated immunity between acute and chronic fungal infected subjects have been well pointed out. While the patient with acute fungal infection has good cell mediated immunity, the patient with chronic fungal infection has poor cell mediated This study was to detect the status of cell mediated immunity in the patie nts with concurrent fungal infections. The authors performed immunologic studies on 32 patients with concurrent fungal infections who had visited the dermatologic clinic of Soonchunhyang University Hospital from July 1982 to June 1983. The results were summarized as follows; 1. The sex ratio of male to female patie nts was 30: 2, and 71.9% of all patients showed I n the fourth and fifth decades. 2. The most prevalent concurrent superficial fungal infection revealed tinea pedis with tinea cruris (65.6%), and all patients had tinea pedis. 3. Positive immediate hypersensitivity reaction was observed only in patients with concurrent fungal infection by trichophytin(87.5%). 4. For the delayed hypersensitivity reaction, the mean skin reaction scores to PPD, candidin, trichophytin were 1.58, 2.78, 0.66 respectively in 32 patients with concurrent fungal infection and 1.89, 2.47, 1.50 respectively in 17 controls, but the statistically significant only in trichophytin (p <0.05). 5. The mean percentage of total and active T cell counts in peripheral blood were 55.2%, 23.9% respectively in 18 patients, and 64.0%, 29.8% in controls ( p < 0.05). There was a significant decrease of T-cell count in patients with concurrent fungal infecti ons. So there was a significant decrease of cell mediated immunity In patients with concurrent fungal infection specifically only in trichophytin.