Dietary germanium biotite supplementation enhances the induction of antibody responses to foot-and-mouth disease virus vaccine in pigs

다국어 초록 (Multilingual Abstract)

We evaluated the potential ability of germanium biotite(GB) to stimulate the production of antibodies specific forfoot-and-mouth disease virus (FMDV). To this aim, wemeasured the total FMDV-specific antibody responses andIgM production after vaccination against FMD bothexperimentally and in the field. GB supplementation withFMDV vaccination stimulated the production of anti-FMDVantibodies, and effectively increased IFN-γ and TNF-αlevels. These results suggest that GB may be a novelalternative feed supplement that can serve as a boosting agent and an immunostimulator for increasing the efficacyof FMDV vaccination in pigs.

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