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      정신건강의학과 개방병동 입원 환자의 진단군별 약물 처방 경향 변화 : 경기도 소재 일 대학병원에서의 11년 비교 연구 = Changes in Psychotropic Prescription Patterns in Patients Admitted to an Open Psychiatric Ward : Eleven-Year Comparison in a University Hospital in Gyeonggi-Do

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      https://www.riss.kr/link?id=A102107754

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      다국어 초록 (Multilingual Abstract)

      Objectives This study investigated the patterns of psychotropic medications prescribed to patients admitted to an open psychiatric ward. Methods We reviewed 4282 medical records of patients who were discharged from an open psychiatric ward from May 2003 through April 2014. Data were collected on each patient's age, sex, length of hospital stay, number of past admissions, discharge diagnosis, and kinds and dosages of psychotropic medications at discharge. Results Among the 1384 male and 2898 female patients, 3.56 psychotropic medications were prescribed on average, with the number increasing across years, from 3.30 in 2003-2008 to 3.76 in 2009-2014. Prescription rates of antipsychotics, anxiolytics, and hypnotics significantly increased in patients with depressive disorders, bipolar disorders, anxiety disorders, delirium, dementia, and amnestic and other cognitive disorders. Only lithium prescription rates decreased significantly. Prescriptions for two or more anxiolytics and antipsychotics increased during the survey years, while antidepressant polypharmacy rates decreased. Conclusions Recently, there has been a significant increase in the number of psychotropic medications prescribed, including antipsychotics, anxiolytics, and hypnotics. Caution should be exercised when prescribing medications to avoid cost increases and the risk of side effects, with uncertain gains in the quality of care.
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      Objectives This study investigated the patterns of psychotropic medications prescribed to patients admitted to an open psychiatric ward. Methods We reviewed 4282 medical records of patients who were discharged from an open psychiatric ward from May 20...

      Objectives This study investigated the patterns of psychotropic medications prescribed to patients admitted to an open psychiatric ward. Methods We reviewed 4282 medical records of patients who were discharged from an open psychiatric ward from May 2003 through April 2014. Data were collected on each patient's age, sex, length of hospital stay, number of past admissions, discharge diagnosis, and kinds and dosages of psychotropic medications at discharge. Results Among the 1384 male and 2898 female patients, 3.56 psychotropic medications were prescribed on average, with the number increasing across years, from 3.30 in 2003-2008 to 3.76 in 2009-2014. Prescription rates of antipsychotics, anxiolytics, and hypnotics significantly increased in patients with depressive disorders, bipolar disorders, anxiety disorders, delirium, dementia, and amnestic and other cognitive disorders. Only lithium prescription rates decreased significantly. Prescriptions for two or more anxiolytics and antipsychotics increased during the survey years, while antidepressant polypharmacy rates decreased. Conclusions Recently, there has been a significant increase in the number of psychotropic medications prescribed, including antipsychotics, anxiolytics, and hypnotics. Caution should be exercised when prescribing medications to avoid cost increases and the risk of side effects, with uncertain gains in the quality of care.

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      참고문헌 (Reference)

      1 윤보현, "한국형 양극성 장애 약물치료 알고리듬 2014: 총론" 대한정신약물학회 25 (25): 43-56, 2014

      2 서호준, "주요 우울장애 입원환자에서 약물 사용의 변화: 일 대학병원에서 2001년과 2006년의 비교" 대한정신약물학회 18 (18): 399-407, 2007

      3 황인환, "조현병 환자의 입원 치료시 약물처방 경향의 변화 : 일 대학병원에서 1996~2000년과 2006~2010년의 차이 비교" 대한생물정신의학회 21 (21): 49-56, 2014

      4 권준수, "일 대학병원에서 정신분열병 외래환자의 약물사용 경향" 대한신경정신의학회 42 (42): 2003

      5 한규만, "근거중심 한국형 우울증 약물학적 치료지침, 개정판(III) : 항우울제의 증량, 교체, 병합 및 강화요법" 대한신경정신의학회 52 (52): 386-401, 2013

      6 Thase ME, "What role do atypical antipsychotic drugs have in treatment-resistant depression?" 63 : 95-103, 2002

      7 Mond J, "Use of antipsychotic medications in Australia between July 1995 and December 2001" 37 : 55-61, 2003

      8 Stephenson CP, "Trends in the utilisation of psychotropic medications in Australia from 2000 to 2011" 47 : 74-87, 2011

      9 Kales HC, "Trends in antipsychotic use in dementia 1999-2007" 68 : 190-197, 2011

      10 Souery D, "Treatment resistant depression: methodological overview and operational criteria" 9 : 83-91, 1999

      1 윤보현, "한국형 양극성 장애 약물치료 알고리듬 2014: 총론" 대한정신약물학회 25 (25): 43-56, 2014

      2 서호준, "주요 우울장애 입원환자에서 약물 사용의 변화: 일 대학병원에서 2001년과 2006년의 비교" 대한정신약물학회 18 (18): 399-407, 2007

      3 황인환, "조현병 환자의 입원 치료시 약물처방 경향의 변화 : 일 대학병원에서 1996~2000년과 2006~2010년의 차이 비교" 대한생물정신의학회 21 (21): 49-56, 2014

      4 권준수, "일 대학병원에서 정신분열병 외래환자의 약물사용 경향" 대한신경정신의학회 42 (42): 2003

      5 한규만, "근거중심 한국형 우울증 약물학적 치료지침, 개정판(III) : 항우울제의 증량, 교체, 병합 및 강화요법" 대한신경정신의학회 52 (52): 386-401, 2013

      6 Thase ME, "What role do atypical antipsychotic drugs have in treatment-resistant depression?" 63 : 95-103, 2002

      7 Mond J, "Use of antipsychotic medications in Australia between July 1995 and December 2001" 37 : 55-61, 2003

      8 Stephenson CP, "Trends in the utilisation of psychotropic medications in Australia from 2000 to 2011" 47 : 74-87, 2011

      9 Kales HC, "Trends in antipsychotic use in dementia 1999-2007" 68 : 190-197, 2011

      10 Souery D, "Treatment resistant depression: methodological overview and operational criteria" 9 : 83-91, 1999

      11 Rush AJ, "Research issues in the study of difficult-to-treat depression" 53 : 743-753, 2003

      12 Zito JM, "Psychotropic practice patterns for youth: a 10-year perspective" 157 : 17-25, 2003

      13 Hogan DB, "Prevalence and potential consequences of benzodiazepine use in senior citizens: results from the Canadian Study of Health and Aging" 10 : 72-77, 2003

      14 Kwon JW, "Prescription pattern and safety of benzodiazepines" National Evidence-based Healthcare Collaborating Agency 1-4, 2013

      15 Baldessarini RJ, "Patterns of psychotropic drug prescription for U.S. patients with diagnoses of bipolar disorders" 58 : 85-91, 2007

      16 Cook JM, "Older patient perspectives on long-term anxiolytic benzodiazepine use and discontinuation:a qualitative study" 22 : 1094-1100, 2007

      17 Comer JS, "National trends in the antipsychotic treatment of psychiatric outpatients with anxiety disorders" 168 : 1057-1065, 2011

      18 Mojtabai R, "National trends in psychotropic medication polypharmacy in office-based psychiatry" 67 : 26-36, 2010

      19 Olfson M, "National patterns in antidepressant medication treatment" 66 : 848-856, 2009

      20 Alexander GC, "Increasing off-label use of antipsychotic medications in the United States, 1995-2008" 20 : 177-184, 2011

      21 Konstantinidis A, "Increase of antipsychotic medication in depressive inpatients from 2000 to 2007: results from the AMSP International Pharmacovigilance Program" 15 : 449-457, 2012

      22 Batstra L, "Holding the line against diagnostic inflation in psychiatry" 81 : 5-10, 2012

      23 Bradley CP, "Factors which influence the decision whether or not to prescribe: the dilemma facing general practitioners" 42 : 454-458, 1992

      24 Bishara D, "Expert opinion on the management of behavioural and psychological symptoms of dementia (BPSD) and investigation into prescribing practices in the UK" 24 : 944-954, 2009

      25 Peters SM, "Demographic and clinical factors associated with benzodiazepine prescription at discharge from psychiatric inpatient treatment" 37 : 595-600, 2015

      26 Fava M, "Definition and epidemiology of treatmentresistant depression" 19 : 179-200, 1996

      27 Fleischhacker WW, "Critical review of antipsychotic polypharmacy in the treatment of schizophrenia" 17 : 1083-1093, 2014

      28 Skrbo A, "Classification of drugs using the ATC system (Anatomic, Therapeutic, Chemical Classification) and the latest changes" 58 (58): 138-141, 2004

      29 Yatham LN, "Canadian Network for Mood and Anxiety Treatments (CANMAT)and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2013" 15 : 1-44, 2013

      30 Billioti de Gage S, "Benzodiazepine use and risk of dementia: prospective population based study" 345 : e6231-, 2012

      31 Bartlett G, "Association between risk factors for injurious falls and new benzodiazepine prescribing in elderly persons" 10 : 1-, 2009

      32 Seo JJ, "Anxiolytic-like effects of obovatol isolated from Magnolia obovata: involvement of GABA/benzodiazepine receptors complex" 31 : 1363-1369, 2007

      33 Correll CU, "Antipsychotic polypharmacy: a survey study of prescriber attitudes, knowledge and behavior" 131 : 58-62, 2011

      34 Gill SS, "Antipsychotic drug use and mortality in older adults with dementia" 146 : 775-786, 2007

      35 Medco Health Solutions, "America’s State of Mind Report" Medco Health Solutions 2011

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2026 평가예정 재인증평가 신청대상 (재인증)
      2020-01-01 평가 등재학술지 유지 (재인증) KCI등재
      2017-01-01 평가 등재학술지 유지 (계속평가) KCI등재
      2013-01-01 평가 등재 1차 FAIL (등재유지) KCI등재
      2010-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2007-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2006-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2004-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.19 0.19 0.19
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.14 0.15 0.475 0
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