모유두세포의 배양에 관한 연구 = Culture of Dermal Papilla Cells모유두세포의 배양에 관한 연구

다국어 초록 (Multilingual Abstract)

Background : Dermal papilla cells, which are mesenchyral components of the hair bulb are considered to play a fundamental role in the inductior hair growth. Objective : We studied how to establish a method of cuku e of dermal papilla cells. Methods : With human scalp tissue, we cultured dermal pipilla cells and identified them under the double-contrat microscopy and observed the epassion of eactin. Results : In vitro they spread slowly, initially as a moayer, and eventually formed multilayered paralled anys. At the edges of expanding colonies the cells were large and flattened and showed a tendency to form clumps. They expressed a-actin which is thought to be a marker of papilla cells, typeIII, typeIV colagen and laminin. Conclusion : These results suggest that using the female papilla cells, specially differentiated fibroblast, may be useful for the study of hau growth. (Kor J Dermatol 1995; 33(1); 28-32)