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      KCI등재 SCOPUS SCIE

      Graphene Films Show Stable Cell Attachment and Biocompatibility with Electrogenic Primary Cardiac Cells

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      https://www.riss.kr/link?id=A104830260

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      다국어 초록 (Multilingual Abstract)

      Graphene has attracted substantial attention due to its advantageous materialistic applicability. In the present study, we tested the biocompatibility of graphene films synthesized by chemical vapor deposition with electrogenic primary adult cardiac cells (cardiomyocytes) by measuring the cell properties such as cell attachment, survival, contractility and calcium transients. The results show that the graphene films showed stable cell attachment and excellent biocompatibility with the electrogenic cardiomyocytes, suggesting their useful applications for future cell biology studies.
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      Graphene has attracted substantial attention due to its advantageous materialistic applicability. In the present study, we tested the biocompatibility of graphene films synthesized by chemical vapor deposition with electrogenic primary adult cardiac c...

      Graphene has attracted substantial attention due to its advantageous materialistic applicability. In the present study, we tested the biocompatibility of graphene films synthesized by chemical vapor deposition with electrogenic primary adult cardiac cells (cardiomyocytes) by measuring the cell properties such as cell attachment, survival, contractility and calcium transients. The results show that the graphene films showed stable cell attachment and excellent biocompatibility with the electrogenic cardiomyocytes, suggesting their useful applications for future cell biology studies.

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      참고문헌 (Reference)

      1 Jo, G, "Tuning of a graphene- electrode work function to enhance the efficiency of organic bulk heterojunction photovoltaic cells with an inverted structure" 97 : 213301-, 2010

      2 Geim, A.K, "The rise of graphene" 6 : 183-191, 2007

      3 Li, N, "The promotion of neurite sprouting and outgrowth of mouse hippocampal cells in culture by graphene substrates" 32 : 9374-9382, 2011

      4 Bird, S.D, "The human adult cardiomyocyte phenotype" 58 : 423-434, 2003

      5 Park, C. S., "Targeted ablation of the histidine-rich Ca2+-binding protein (HRC) gene is associated with abnormal SR Ca2+-cycling and severe pathology under pressure-overload stress" DR DIETRICH STEINKOPFF VERLAG 108 : 344-, 2013

      6 Freire, E, "Structure of laminin substrate modulates cellular signaling for neuritogenesis. J. Cell Sci. 115, 4867-4876. Geim, A.K. (2009). Graphene: status and prospects" 324 : 1530-1534, 2009

      7 Beck, K, "Structure and function of laminin: anatomy of a multidomain glycoprotein" 4 : 148-160, 1990

      8 Bitounis, D, "Prospects and challenges of graphene in biomedical applications" 25 : 2258-2268, 2013

      9 Oh, J.G, "PICOT increases cardiac contractility by inhibiting PKCzeta activity" 53 : 53-63, 2012

      10 Duch, M.C, "Minimizing oxidation and stable nanoscale dispersion improves the biocompatibility of graphene in the lung" 11 : 5201-5207, 2011

      1 Jo, G, "Tuning of a graphene- electrode work function to enhance the efficiency of organic bulk heterojunction photovoltaic cells with an inverted structure" 97 : 213301-, 2010

      2 Geim, A.K, "The rise of graphene" 6 : 183-191, 2007

      3 Li, N, "The promotion of neurite sprouting and outgrowth of mouse hippocampal cells in culture by graphene substrates" 32 : 9374-9382, 2011

      4 Bird, S.D, "The human adult cardiomyocyte phenotype" 58 : 423-434, 2003

      5 Park, C. S., "Targeted ablation of the histidine-rich Ca2+-binding protein (HRC) gene is associated with abnormal SR Ca2+-cycling and severe pathology under pressure-overload stress" DR DIETRICH STEINKOPFF VERLAG 108 : 344-, 2013

      6 Freire, E, "Structure of laminin substrate modulates cellular signaling for neuritogenesis. J. Cell Sci. 115, 4867-4876. Geim, A.K. (2009). Graphene: status and prospects" 324 : 1530-1534, 2009

      7 Beck, K, "Structure and function of laminin: anatomy of a multidomain glycoprotein" 4 : 148-160, 1990

      8 Bitounis, D, "Prospects and challenges of graphene in biomedical applications" 25 : 2258-2268, 2013

      9 Oh, J.G, "PICOT increases cardiac contractility by inhibiting PKCzeta activity" 53 : 53-63, 2012

      10 Duch, M.C, "Minimizing oxidation and stable nanoscale dispersion improves the biocompatibility of graphene in the lung" 11 : 5201-5207, 2011

      11 Jo, G, "Largescale patterned multi-layer graphene films as transparent conducting electrodes for GaN light-emitting diodes" 21 : 175201-, 2010

      12 Yarnitzky, T, "Laminin is required for heart, somatic muscles, and gut development in the Drosophila embryo" 169 : 609-618, 1995

      13 Gregory, K.N, "Histidine-rich Ca binding protein: a regulator of sarcoplasmic reticulum calcium sequestration and cardiac function" 40 : 653-665, 2006

      14 Hess, L.H, "Graphene transistor arrays for recording action potentials from electrogenic cells" 23 : 5045-5049, 2011

      15 Kalbacova, M, "Graphene substrates promote adherence of human osteoblasts and mesenchymal stromal cells" 48 : 4323-4329, 2010

      16 Cohen-Karni, T, "Graphene and nanowire transistors for cellular interfaces and electrical recording" 10 : 1098-1102, 2010

      17 Lee, S., "Enhanced Charge Injection in Pentacene Field-Effect Transistors with Graphene Electrodes" WILEY-V C H VERLAG GMBH 23 (23): 100-100, 2011

      18 Kwon, S.J, "Characterization of junctate- SERCA2a interaction in murine cardiomyocyte" 390 : 1389-1394, 2009

      19 Jihyun Yoon, "Bone Marrow-derived Side Population Cells are Capable of Functional Cardiomyogenic Differentiation" 한국분자세포생물학회 25 (25): 216-223, 2008

      20 Mao, X, "Bipyrenefunctionalized graphene as a “turn-on” fluorescence sensor for manganese(II) ions in living cells" 5 : 592-597, 2013

      21 Sahni, D, "Biocompatibility of pristine graphene for neuronal interface. J. Neurosurg" 11 : 575-583, 2013

      22 Ryoo, S. R., "Behaviors of NIH-3T3 Fibroblasts on Graphene/Carbon Nanotubes: Proliferation, Focal Adhesion, and Gene Transfection Studies" AMER CHEMICAL SOC 4 (4): 6587-6598, 2010

      23 Yamamoto, T, "Abnormal Ca2+ release from cardiac sarcoplasmic reticulum in tachycardia-induced heart failure" 44 : 146-155, 1999

      24 Kahng, Y. H., "A study of graphene films synthesized on nickel substrates: existence and origin of small-base-area peaks" IOP PUBLISHING LTD 22 (22): 045706-, 2011

      25 민달희, "A New Helicase Assay Based on Graphene Oxide for Anti-Viral Drug Development" 한국분자세포생물학회 35 (35): 269-273, 2013

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      2023 평가예정 해외DB학술지평가 신청대상 (해외등재 학술지 평가)
      2020-01-01 평가 등재학술지 유지 (해외등재 학술지 평가) KCI등재
      2012-11-07 학술지명변경 한글명 : 분자와 세포 -> Molecules and Cells KCI등재
      2008-01-01 평가 SCI 등재 (등재유지) KCI등재
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      1998-07-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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