Development of a Motor Driven Automatic Device Performing Simulataneous Sternothoracic Cardiopulmonary Resuscitation and Its Hemodynamic Effects in An Animal Model of Cardiac Arrest = Development of a Motor Driven Automatic Device Performing Simulataneous Sternothoracic Cardiopulmonary Resuscitation and Its Hemodynamic Effects in An Animal Model of Cardiac Arrest

다국어 초록 (Multilingual Abstract)

Introduction: A motor driven automatic CPR device can enhance its utility with portability and ease of use. The aim of this study was to develop a motor driven automatic CPR device and investigate its hemodynamic effect compared to standard manual CPR in an animal model of ventricular fibrillation. Material & Methods: A battery-powered, motor driven automatic device performing simultaneous sternothoracic CPR was developed. To assess hemodynamic efficacy, 20 male pigs were randomized to receive standard CPR (S-CPR) or CPR with an automatic device (A-CPR) after 5 minutes of V fib.5 minutes of BLS was performed and followed by 10 minutes of ACLS including defibrillation and epinephrine. Aortic pressure (AP), coronary perfusion pressure (CPP), carotid blood flow (CBF), end-tidal carbon dioxide tension (ETCO2), defibrillation success, and 2 hour survival were compared Results: Systolic, mean APs, and CBF were higher in A-CPR group than S-CPR group during BLS and ACLS (systolic AP: 101±76 vs.163±64 mmHg, p=0.001; mean AP: 37±22 vs.60±20 mmHg, p=0.000; CBF: 50±48 vs. 100±63 ml/min, p=0.000). The other parameters were not different between two groups. Conclusion: A battery-powered, motor driven automatic device performing simultaneous sternothoracic CPR results in higher systolic blood pressure, mean blood pressure, and carotid blood flow compared to S-CPR.