만성 이하선 타액선염 환자에서 타액관 스테로이드 세척술의 유용성 = Usefulness of Stensen’s Duct Steroid Irrigation in Patients With Chronic Sialadenitis of the Parotid Gland

다국어 초록 (Multilingual Abstract)

Background and Objectives Inflammatory and obstructive diseases of the salivary glandscan cause recurrent pain, swelling, and dry mouth, significantly affecting the quality of life. Inmost cases, symptoms improve after medical treatment, but if symptoms persist or recur, othertreatment methods should be considered. The purpose of this study was to evaluate the thera-peutic effect of salivary duct steroid irrigation in refractory chronic sialadenitis.
Subjects and Method A retrospective study was conducted on 19 patients who underwentStensen’s duct steroid irrigation from January 2016 to December 2021. All patients enrolled instudy had no improvement of symptoms after medical treatment. The clinical characteristicsincluding etiology, location, symptom duration, underlying disease, treatment response andcomplications of the patients were analyzed.
Results Stensen’s duct steroid irrigation was effective in 12 of 19 patients (63%), of which 5(26%) showed complete disappearance of symptoms. There was no difference in the treatmenteffect by etiology. The rate of non-response to treatment was high when the symptom durationwas more than one year. Temporary parotid gland swelling occurred in two patients after irri-gation, while other side effects such as bleeding and infection did not occur.
Conclusion Salivary duct steroid irrigation is a simple and safe procedure, which may beconsidered as a treatment method for medically refractory chronic sialadenitis.

참고문헌 (Reference)

1 Kim EM, "Ultrasound-guided sialo-irrigation for the treatment of chronic sialodochitis with sialolithiasis" 37 (37): 345-351, 2021

2 Kim JE, "Therapeutic effect of intraductal saline irrigation in chronic obstructive sialadenitis" 20 (20): 86-, 2020

3 이채나 ; 김조은 ; 허경회 ; 이원진 ; 허민석 ; 이삼선 ; 최순철, "Therapeutic effect of intraductal irrigation of the salivary gland: A technical report" 대한영상치의학회 47 (47): 123-127, 2017

4 Schwarz D, "The positive effect of sialendoscopy with irrigation lavage for sialadenitis without sialolithiasis or stenosis" 80 (80): 271-276, 2018

5 Qi S, "Sialoendoscopic and irrigation findings in chronic obstructive parotitis" 115 (115): 541-545, 2005

6 Lele SJ, "Sialendoscopy with intraductal steroid irrigation in patients with sialadenitis without sialoliths" 98 (98): 291-294, 2019

7 Gilat H, "Radioiodine therapy induced sialadenitis versus chronic idiopathic sialadenitis—Presentation and outcomes" 43 (43): 2724-2730, 2021

8 Hernandez S, "Parotitis and sialendoscopy of the parotid gland" 49 (49): 381-393, 2016

9 Chen YC, "Office-based salivary gland ductal irrigation in patients with chronic sialoadenitis : A preliminary study" 120 (120): 318-326, 2021

10 Rice JB, "Long-term systemic corticosteroid exposure : A systematic literature review" 39 (39): 2216-2229, 2017

11 Rahmati R, "Is sialendoscopy an effective treatment for obstructive salivary gland disease?" 123 (123): 1828-1829, 2013

12 Aframian DJ, "Improvement of dry mouth following intraductal irrigation of salivary glands" 25 (25): 1735-1743, 2019

13 이채나 ; Lee Ari ; Kim Hak-Sun ; Choi Yoon Joo ; 전국진 ; 한상선, "Efficacy of corticosteroid ductal irrigation in acute salivary gland inflammation induced in a rat model" 대한영상치의학회 52 (52): 61-66, 2022

14 Izumi M, "Corticosteroid irrigation of parotid gland for treatment of xerostomia in patients with Sjögren’s syndrome" 57 (57): 464-469, 1998

15 Capaccio P, "Combined interventional sialendoscopy and intraductal steroid therapy for recurrent sialadenitis in Sjögren’s syndrome : Results of a pilot monocentric trial" 43 (43): 96-102, 2018