Micro-CT를 이용한 열처리 해면골 시편의 구조적 특성 분석 = Structural Analysis of Heat Treated Trabecular Bone Scaffolds using Micro-CT

다국어 초록 (Multilingual Abstract)

Heat-treated porcine trabecular bone scaffold is known to be an ideal xenograft in that it has great physical and chemical properties as a bone graft for application in tissue engineering. The aim of this study was to investigate the various structural changes of a porcine trabecular bone scaffold before and after heat treatment. Porcine trabecular bone scaffolds were prepared from porcine sternum, and were heat treated using 400oC, 600oC, 800oC, and 1000oC. To examine their structural changes after heat treatment, the scaffolds were scanned by micro-CT to acquire the various trabecular bone parameters before and after heat treatment. Results showed that bone volume as well as bone surface of porcine trabecular bone scaffolds statistically decreased with increasing heat treatment. Also, trabecular thickness of the scaffolds increased with heat treatment. Our results indicate that porcine trabecular bone are contracted during heat treatment and thus we should consider the effects of structural deformation when preparing heat-treated porcine bone grafts for tissue engineering applications.

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