다발성 낭종을 동반한 면포 모반 = Nevus Comedonicus with Multiple Cyst

다국어 초록 (Multilingual Abstract)

Purpose: Nevus comedonicus is a rare disease involving
abnormal development of the pilosebaceous unit, clinically
appearing confluent clusters of open comedones. It is
characterized by follicular epidermic invaginations filled with
keratin, with atrophic pilose or sebaceous structures which
are open to the lower pole of the invagination. We report
a child with inflammatory pustules and cysts correlated to
the nevus comedonicus.
Methods: A 15-month-old girl was referred for treatment
of a nevus comedonicus that has been developed since
birth. There were periodic episodes of erythema and
swelling of the plaque. The patient had treated previously
with retinoid cream for 2 weeks without obvious benefit at
dermatology clinic. We excised the nevus comedonicus
with Y-shape leaving some lesions.
Results: When we incised skin, we could see multiple
large whitish cysts beneath the nevus comedonicus.
Histopathologic findings showed deep invagination of
epidermis filled with keratin plugs, keratinous cyst in the
dermis, rudimentary hair follicle.
Conclusion: We treated rare nevus comedonicus with
multiple large cysts as surgical excision.

참고문헌 (Reference)

1 박은주, "표피박리성 과각화증을 보인 면포성 모반 1예" 대한피부과학회 42 (42): 1065-1068, 2004

2 Kirtak N, "Ozgoztasi O: Extensive inflammatory nevus comedonicus involving half of the body" 43 : 434-, 2004

3 Kurokawa I, "Isoda K-i, Yamanaka K-i, Mizutani H, Tsubura A: Cytokeratin and filaggrin expression in nevus comedonicus" 34 : 388-, 2006

4 Disen AZ, "Benign epithelial tumors, Hamartomas, and hyperplasias. In: Fitzpatrick’s dermatology in general medicine, 7th ed" Mcgrawhill 1059-, 2008