고 칼슘 투여가 성장기 흰쥐의 골 성장과 대사에 미치는 영향 = The Effect of High Calcium on the Growth and Merabolism of Bones in Growing Rats

다국어 초록 (Multilingual Abstract)

This study examined the effect of excess calcium(Ca) on bioavailability, bone growth, and turnover of bones in growing rats. 21 weanling female SD rats were fed normal Ca diet for 3 weeks. Then animals were assigned randomly to one of three groups and were fed one of three levels of Ca as normal(0.5%), high(1.0%), or excess(1.5%). Feces and urine were collected during the last 3 days of treatment. Final body weight and average food intake were not affected by the levels of dietary Ca. High and excess Ca intakes reduced the apparent absorption of Ca. Ca contents in kidney were increased by high and excess Ca, however kidney function was not impaired. While Ca contents in bones were increased by high and excess Ca intakes the weights, lengths, and breaking forces of the bones were not affected by increased Ca intakes. These results indicate bone growth and strength would not be favorably affected by high Ca intakes, though, the long term effect of increased Ca contents in bone requires further examination.