농산물 중 Fluxametamid 분석법 개발 = An Analytical Method for Fluxametamid Residues in Food Matrix

다국어 초록 (Multilingual Abstract)

Fluxametamid (IUPAC name: 4-[5-(3, 5-dichlorophenyl)-5-(trifluoromethyl)- 4, 5-dihydro-1, 2-oxazol-3-yl]-N-[(methoxyimino)methyl]-2-methylbenzamide) is isoxazoline insecticide and acarcide. An analytical method for the determination of fluxametamid residue in foods was developed as Ministry of Food and Drug Safety (MFDS) method. After extracting with acetonitrile, samples were partitioned and concentrated with dichloromethane. To remove the interferences, silica SPE cartridge was performed before LC-MS/MS (Liquid Chromatography-Tandem Mass Spectrometry) analysis with C18 column. Five agricultural commodities (mandarin, potato, soybean, brown rice, and hot pepper) were used as group representative to verify. The linear matrix-matched calibration curve were confirmed (coefficient of determination > 0.99 with calibration range 0.01-2.5 mg/kg). Fluxametamid from sample with recoveris range from 82.24~115.27%. The precision were also shown less than 9.54% for all five samples.
These spiked recoveries fall well within the recommened mean values in CODEX guideline for residue analysis (CAC/GL 40). Thus this method successfully processes food samples for Fluxametamid utilizing LC-MS/MS method.