殺蟲劑의 白鼠에 對한 急性 毒性에 關하여 = A Study on Acute Toxicity of Dibrom phosphate, Carbamate and Pyridyl phoshate on Mice

다국어 초록 (Multilingual Abstract)

This paper presented that acute toxicity of dibrom phophate, carbamate and pyridyl phophate among various insecticides which were commonly used in Korea was observed on mice.
The results obtained are summarized as follows:
Oral toxic effects with convulsion, lethalgy, vomiting and incontinence of urine, and death were rapidly appeared. And soon after that that was gradually diminished within about 12 hours. Carbamate had the strongest toxicity (LD_50:105mg/kg) and that of pyridyl phophate was persisting effects but had the weakest of toxicity (LD_50:340mg/kg).
Dermal toxic effects were rather slower and prolonger than that of oral. The symptoms such as convulsion, vomiting or incontinece of urine were rarely observed but severe weakness was quite distinctly observed when compaired to the oral toxicty. Dermal toxicity of pyridl phosphate (LD_50: 130mg/kg) revealed to be relatively stronger than those of dibrom phophate (LD_50: 200mg/kg) and carbamate (LD_50: 130mg/kg) which were rather weak.
Intraperitoneal toxic effects induced convulsion and severe weakness. Carbamate showed stronger toxicity (LD_50: 17mg/kg) than dibrom phosphate (LD_50: 55mg/kg) and pyridyl phosphate (LD_50: 50mg/kg). As a whole, this effect surpassed the oral or dermal toxicity.