약용 식물 추출물의 항산화 활성 검색 = Screening for Antioxidant Activity of Plant Medicinal Extracts

다국어 초록 (Multilingual Abstract)

The antioxidant activities of 80% methanol extracts obtained from 118 medicinal plants were tested through the evaluation of DPPH and superoxide anion radicals scavenging activity. Methanol extracts of Sophora japonica (76.9%) and Camptotheca acuminata Dence (50.9%) were found to have more than 50% DPPH radical scavenging activity while those of Perilla frutescens (37.2%), Amomum costatum (34.9%), Prunus ansu (33.2%), Mentha arvensis (32.3%), Serratula koreana (32.2%), Eriobotrya japonica (30.5%), and Artemisia asiatica (30.5%) showed more than 30% scavenging activity. Even though all of the commercial antioxidants didn’t show superoxide anion radical activity, Mentha arvensis (87.7%), Eriobotrya japonica (84.9%), Amomum costatum (82.9%), Camptotheca acuminata Dence (82.1%) showed more than 80% scavenging activity. Mentha arvensis, Eriobotrya japonica, Amomum costatum, Camptotheca acuminata Dence showed strong antioxidative activity in the both DPPH and superoxide anion radical scavenging activities.

참고문헌 (Reference)

1 "Toxicology and biochemistry of butylatedhydroxy anisole and butylated hydroxytoluene. J. Am. OilChem. Soc. 52" 59-63, 1975

2 "Studies on the anti-aging ofKorean Ginseng. Korean J. Food Sci. Technol. 17" 506-515, 1985

3 "Roleof metals in oxygen radical reactions. J. Free Radicals Biol.Med. 1" 3-25, 1985

4 "Proteins damaged byoxygen radicals are rapidly degraded in extracts of red bloodcells. J. Biol. Chem. 262" 8227-8234, 1987

5 "Nutrition and health aspects of freeradicals and antioxidants. Food Chem. Toxicol. 32" 671-683, 1994

6 "Isolation of natural antioxidants from the root ofZingiber officinale. R. J. Korean Soc. Agric. Chem. Biotechnol.44" 44 : 202-205, 2001

7 "Isolation and Structure Determination of Antioxidantsfrom the Root of Paeonia lactiflora. J. Korean Soc. Agric.Chem. Biotechnol. 42" 42 : 170-175, 1999

8 "InHandbook of free radicals and antioxidants in biomedicine.CRC Press" 1989

9 "In Phenolic compounds in food and their effects onhealth" 1992

10 "In Free radicals in biology V. AcademicPress" 255-275, 1982

11 "Identification and antioxidant activity of novel chlorogenic acidderivatives from bamboo" 49 : 4646-4655, 2001

12 "Antioxidant determination by the use of astable free radical. Nature 181" 1199-1200, 1958

13 "Activation of pharmacologic agents to radical intermediates.Implications for the role of free radicals in drug action andtoxicity. Biochem. Pharmacol. 31" 3335-3346, 1982