고압 펌프 및 피에조 인젝터에 의한 약물 젯팅 실험

다국어 초록 (Multilingual Abstract)

This study proposes a new mechanism for needle-free drug injection into the skin of agricultural animals that can be simple, lightweight and high response characteristic, for the delivery of proteins or vaccines. Jet injectors, which deliver drugs into the skin using compressed springs or compressed gas, provide a needle-free method of conventional transdermal drug delivery. However, the compressed spring or gas type injector has the drawbacks of high weightand impact noise. On the other hand, the high pressure injection device using a high pressure pump and an on-off valve has the advantage that it is smaller than the noise of spring or gas injectors. For this reason, we propose a mechanism that consists of a high pressure pump, an accumulator, an on-off valve and an injection nozzle. We tested a commercial injector- a compressed gas injector - and the impact gun type injector - a compressed spring injector - and used them to verify new specifications. The accuracy of injection was measured with an electronic weight balancer. Finally, the proposed mechanism was evaluated their suitability for needle-free drug injection based on results of the analysis and comparison of all the injectors.

목차 (Table of Contents)

• Abstract
• 1. 서론
• 2. 고속 압전 ON/OFF 밸브
• 3. 실험모델의 젯팅 력(force) 측정
• 4. 실험모델의 젯팅 량(volume) 측정
• 5. 결론
• 참고 문헌