난자 공여를 이용한 체외수정시술에 관한 연구 = Studies on Oocyte Donation in IVF Program

다국어 초록 (Multilingual Abstract)

It has been well recognized that both the synchronization of luteinizing hormone(LH) surge between the donor and the recipient for normally cycling women and the complex steroid replacement regimen given on a sequential and incremental basis for women with primary or secondary ovarian failure are two important aspects in oocyte donation. In oocyte donation program at our center, a simplified hormonal regimen applicable both to normally cycling women and to those with ovarian failure which consisted of administering 2 mg estradiol(E2) valerate orally three times daily augmented with 100 mg progesterone(P) in oil intramuscularly daily starting on the day preceding the oocyte retrieval from the donor was utilized. From July 1988 to April 1990, 15 cycles of oocyte donation program in 13 infertile patients were undertaken and 6 patients succeeded in pregnancy with the pregnancy rate of 46.2% per patient and 40.0% per cycle.