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      뇌졸중 이후의 이상지혈증의 관리 = Management of Dyslipidemia after Stroke

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      https://www.riss.kr/link?id=A108210251

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      다국어 초록 (Multilingual Abstract)

      Dyslipidemia is a major risk factor for stroke, following hypertension, diabetes, and smoking. Treatment of dyslipidemia is important for the prevention and treatment of various vascular diseases, including stroke, coronary artery disease, and peripheral vascular disease. Statins, ezetimibe, and proprotein convertase subtilisinkexin type 9 (PCSK9) inhibitors have been shown to reduce the risk of stroke and cardiovascular disease in previous studies. When prescribing dyslipidemia drugs for secondary prevention of stroke, the combination, type, and dose of dyslipidemia drugs should be appropriately selected according to the patient's comorbidity and stroke subtype. In the case of statins, highintensity statin administration should be considered, but it is essential to take into account side effects, comorbidities, and individual characteristics of each patient.
      If the target low density lipoproteincholesterol level is not reached or inappropriate drug dosing due to the side effects of statins, ezetimibe or a PCSK9 inhibitor may be considered. Finally, statin discontinuation due to improper judgment may be detrimental to the patient in the longterm view.
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      Dyslipidemia is a major risk factor for stroke, following hypertension, diabetes, and smoking. Treatment of dyslipidemia is important for the prevention and treatment of various vascular diseases, including stroke, coronary artery disease, and periphe...

      Dyslipidemia is a major risk factor for stroke, following hypertension, diabetes, and smoking. Treatment of dyslipidemia is important for the prevention and treatment of various vascular diseases, including stroke, coronary artery disease, and peripheral vascular disease. Statins, ezetimibe, and proprotein convertase subtilisinkexin type 9 (PCSK9) inhibitors have been shown to reduce the risk of stroke and cardiovascular disease in previous studies. When prescribing dyslipidemia drugs for secondary prevention of stroke, the combination, type, and dose of dyslipidemia drugs should be appropriately selected according to the patient's comorbidity and stroke subtype. In the case of statins, highintensity statin administration should be considered, but it is essential to take into account side effects, comorbidities, and individual characteristics of each patient.
      If the target low density lipoproteincholesterol level is not reached or inappropriate drug dosing due to the side effects of statins, ezetimibe or a PCSK9 inhibitor may be considered. Finally, statin discontinuation due to improper judgment may be detrimental to the patient in the longterm view.

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      참고문헌 (Reference)

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      6 Shah RV, "Statins and risk of new-onset diabetes mellitus" 126 : e282-e284, 2012

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      2 Ganda OP, "Unmet need for adjunctive dyslipidemia therapy in hypertriglyceridemia management" 72 : 330-343, 2018

      3 Fang WT, "The role of statin therapy in the pre-vention of atrial fibrillation : a meta-analysis of randomized controlled trials" 74 : 744-756, 2012

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      6 Shah RV, "Statins and risk of new-onset diabetes mellitus" 126 : e282-e284, 2012

      7 Hackam DG, "Statins and intracerebral hemorrhage : collaborative systematic review and meta-analysis" 124 : 2233-2242, 2011

      8 Goldstein LB, "Statins after intracerebral hemorrhage : to treat or not to treat" 68 : 565-566, 2011

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      42 Casolla B, "Five-year risk of major ischemic and hemorrhagic events after intra-cerebral hemorrhage" 50 : 1100-1107, 2019

      43 Cannon CP, "Ezetimibe added to statin therapy after acute coronary syndromes" 372 : 2387-2397, 2015

      44 Hammersley D, "Ezetimibe : an update on its clinical useful-ness in specific patient groups" 8 : 4-11, 2017

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      65 Tramacere I, "Comparison of statins for secondary prevention in patients with ischemic stroke or transient ischemic attack : a systematic review and network meta-analysis" 17 : 67-, 2019

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      67 Montaner J, "Combination of thrombolysis and statins in acute stroke is safe : results of the STARS randomized trial(stroke treat-ment with acute reperfusion and simvastatin)" 47 : 2870-2873, 2016

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      70 Malhotra K, "Association of statin pretreatment with collateral circulation and final infarct volume in acute ischemic stroke patients : a meta-analysis" 282 : 75-79, 2019

      71 Fauchier L, "Antiarrhythmic effect of statin therapy and atrial fibrillation a meta-analysis of randomized controlled trials" 51 : 828-835, 2008

      72 Schwartz GG, "Alirocumab and cardiovascular outcomes after acute coronary syndrome" 379 : 2097-2107, 2018

      73 Mach F, "Adverse effects of statin therapy: perception vs. the evidence - focus on glucose homeostasis, cognitive, renal and hepatic function, hae-morrhagic stroke and cataract" 39 : 2526-2539, 2018

      74 Amarenco P, "A comparison of two LDL cholesterol targets after ischemic stroke" 382 : 9-, 2019

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      77 Powers WJ, "2018 guidelines for the early management of patients with acute ischemic stroke : a guideline for healthcare professionals from the American Heart Association/American Stroke Association" 49 : e46-e110, 2018

      78 이은정 ; 김현창 ; 김재현 ; 이은영 ; 김병진 ; 김은미 ; 송윤주 ; 임정현 ; 김해진 ; 최성훈 ; 문민경 ; 나진오 ; 박광열 ; 오미선 ; 한상엽 ; 노정현 ; 이경희 ; 이상학 ; 홍순철 ; 정인경, "2018 Guidelines for the management of dyslipidemia" 대한내과학회 34 (34): 723-771, 2019

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      2006-06-20 학술지명변경 한글명 : Journal of the Korean Neurological Association -> 대한신경과학회지 KCI등재
      2006-01-01 평가 등재학술지 유지 (등재유지) KCI등재
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      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.07 0.07 0.07
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.08 0.08 0.245 0.04
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