만성 간질환 환자에 있어서 간초음파소견과 간조직검사와의 비교 = Comparison between Liver Histology and Ultrasonography in Chronic Liver Diseases만성 간질환 환자에 있어서 간초음파소견과 간조직검사와의 비교

다국어 초록 (Multilingual Abstract)

Background/Aims: Real time ultrasound scanning is accepted as the state-of-the-art imaging investigation in patients suspected with liver disease. In focal lesion, numerous studies have confirmed the accuracy of ultrasound scanning in diagnosis and this is also valuable in clinical management, In diffused parenchymal liver diseases, however, the diagnostic value of scanning in diagnosis is less valuable than focal disease. The aim of this study is to examine the clinical value of routine ultrasound examination in patients with parenchymal liver disease. Methods: The results of hepatic ultrasonography and hepatic histology in 278 patients that underwent liver biopsy between January l986 and December l992 were compared with the results ot routine ultrasound examinetion. All liver hiopsies were performed within I month of the ultrasonography. Results: Ultrasound examination revealed a sensitivity and specificity of 54% and 74%, in all cases. Ultrasound examination was highly sensitive for detecting fatty liver(81%) and similar sensitivity (64%) for cirrhosis but less sensitive for detecting chronic hepatitis(45%). Strong correlation was found between the degree of fatty change in histologically and the fine echo pattern of steatosis (p<0.001). Correlations was also between thc degree of hepatic fibrosis and echogenicity(p<0.001), hut hepatic inflammation, necrosis, and cholestasis had no significant correlation with echogenicity. Conclusions: Ultra.onography can be a useful tool in non-invasive prediction of liver histology in steatosis and cirrhosis, hut it is le.s useful in gauging hepatic inflammation, necrosis, and cholestasis. (Korean J Gastroenterol 1995;27: 199 - 205)