Synthesis, Structure, Magnetic Properties and Aqueous Optical Citrate Detection of Chiral Dinuclear Cu^II Complexes

다국어 초록 (Multilingual Abstract)

<P>Two chiral dimeric Cu<SUP>II</SUP> Schiff base complexes, Na<SUB>2</SUB>[Cu(S-lys)<SUB>2</SUB>·(H<SUB>2</SUB>O)<SUB>2</SUB>]·(ClO<SUB>4</SUB>)<SUB>2</SUB> (1) and [Cu(S-ornH)<SUB>2</SUB>·(H<SUB>2</SUB>O)<SUB>2</SUB>]·(ClO<SUB>4</SUB>)<SUB>2</SUB> (2) have been prepared by an easy one-pot method in which the L-lysine and L-ornithine-based Schiff base ligands are generated in situ. These complexes have been characterized by various spectroscopic techniques and single-crystal X-ray diffraction. The molecular structures show that both complexes are indeed dimeric with Cu<SUP>II</SUP> centers that are phenolate-bridged. Variable-temperature magnetic analysis revealed that a strong antiferromagnetic coupling interaction was mediated through the phenolate bridge between the two Cu<SUP>II</SUP> centers. Since these compounds were highly soluble in water, we explored carboxylate sensing capability through colorimetric indicator displacement assays (IDAs). By using pyrocatechol violet (PV) as a displaceable colorimetric indicator, citrate ion selectivity was demonstrated in 100 % water solution in the physiological pH range.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)</P>
<B>Graphic Abstract</B>
<P>Two chiral dimeric Cu<SUP>2+</SUP> complexes 1 and 2 have been prepared by a one pot method in which the L-lysine- and L-ornithine-based Schiff base ligands are generated in situ. Variable-temperature magnetic susceptibility measurements reveal strong antiferromagnetic coupling interactions. Selective citrate ion sensing was enabled through colorimetric indicator displacement assays in water at physiological pH.
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