임상 : 상전두개저 종양 절제술; 전통적인 두개안면절제술과 내시경적 두개안면절제술의 비교 = Resection of Anterior Skull Base Tumors: Comparison of Traditional Craniofacial Resection and Endoscopic Craniofacial Resection

다국어 초록 (Multilingual Abstract)

Tumors of the anterior skull base are rare. Most neurosurgeons and ENT surgeons use traditional craniofacial resection (TCFR) to remove anterior skull base tumors. Recently, endoscopic craniofacial resection (ECFR) also has been used for resection of the tumors of the nasal side; this strategy facilitates superior visualization, avoids facial incisions, and preserves local structures. The purpose of this study was to compare the outcome of these two approaches. A retrospective analysis was conducted to identify patients undergoing resection of anterior skull base tumors between September 1996 and May 2010. Demographic data, pathology, surgical approach, operative time, estimated blood loss, hospital stay, and complications were analyzed. Recurrence and mortality rates were also investigated. Eight patients were managed with ECFR, and 24 patients were treated with TCFR. Differences were observed between the two groups with respect to the operation time, estimated blood loss, and hospital stay. Complications were encountered in 1/8 (12.5%) and 4/24 (16.7%) patients in the ECFR and TCFR groups, respectively. Recurrence was observed in 4/8 (50%) and 10/24 (41.7%) patients in the ECFR and TCFR groups, respectively. Mortality rates were 2/8 (25.0%) and 13/24 (54.2%), in the ECFR and TCFR groups, respectively. Consequently, ECFR was significantly better than TCFR with respect to the operation time, estimated blood loss, and hospital stay. The rate of complications, recurrence, and mortality were not statistically different between the two groups. This comparison suggests that the ECFR approach might be an alternative surgical treatment option for the removal of anterior skull base tumors.