미세 입자 직경과 재질에 따른 모세관 상승된 액체의 젖음 거동에 관한 연구

다국어 초록 (Multilingual Abstract)

Janus particles, named after the Roman god with two faces, are micro/nanoparticles featuring an asymmetric structure that allows for distinct functionalities on each side, enabling synergistic chemical and physical properties. Recently, Janus cells, which are living cells partially coated with drugs, have garnered interest as novel drug delivery systems because they retain native biological characteristics on the uncoated side while allowing efficient payload delivery. However, traditional Janus-particle synthesis methods often require harsh conditions that are unsuitable for living cells. The lower-half occupation of capillary ascended liquid (LOCAL) technique was recently established to address these limitations using capillary flows to achieve selective coating of particles or cells without cytotoxic steps. In this study, the reproducibility and scalability of the LOCAL approach were quantitatively evaluated using polystyrene- and nickel-plated hollow glass microspheres of various diameters with hydrophobic and moderately hydrophilic surface chemistry, respectively. Capillary rise and contact angle analyses demonstrated that regardless of the particle size, coating-solution interfaces consistently formed at predictable polar angles determined by the wetting properties rather than the particle geometry. This confirms the governing role of surface wettability in establishing reproducible lower-half coatings and supports the adaptability of LOCALs for diverse particle and material types in biomedical applications.