Mucinous Adenocarcinoma in a Horseshoe Kidney

다국어 초록 (Multilingual Abstract)

We report here on a case of mucinous adenocarcinoma that probably originated in the renal
pelvis of a horseshoe kidney. A 61-year-old woman presented with a palpable mass in the left
upper quadrant of the abdomen, and this mass had been present for several months. Computed
tomography (CT) revealed a left renal pelvic tumor in the horseshoe kidney. Grossly, a
10×9×8 cm unilocular cystic mass filled with chocolate colored mucinous fluid was seen. A
connection between the cystic mass and the renal pelvis was demonstrated on retrograde
pyelography. Microscopically, the cyst contained anaplastic columnar mucosecretory epithelial
cells. Some atypical cell clusters were freely floating in the mucinous lakes. The histopathological
findings were consistent with mucinous adenocarcinoma. In addition, glandular metaplasia
was noted in the cystic wall. Immunohistochemical assessment of the pelvic adenocarcinoma
revealed the positive expressions of carcinoembryonic antigen (CEA) and cytokeratin
20 (CK20) and a weak positive expression of cytokeratin 7 (CK7).

다국어 초록 (Multilingual Abstract)

We report here on a case of mucinous adenocarcinoma that probably originated in the renal
pelvis of a horseshoe kidney. A 61-year-old woman presented with a palpable mass in the left
upper quadrant of the abdomen, and this mass had been present for several months. Computed
tomography (CT) revealed a left renal pelvic tumor in the horseshoe kidney. Grossly, a
10×9×8 cm unilocular cystic mass filled with chocolate colored mucinous fluid was seen. A
connection between the cystic mass and the renal pelvis was demonstrated on retrograde
pyelography. Microscopically, the cyst contained anaplastic columnar mucosecretory epithelial
cells. Some atypical cell clusters were freely floating in the mucinous lakes. The histopathological
findings were consistent with mucinous adenocarcinoma. In addition, glandular metaplasia
was noted in the cystic wall. Immunohistochemical assessment of the pelvic adenocarcinoma
revealed the positive expressions of carcinoembryonic antigen (CEA) and cytokeratin
20 (CK20) and a weak positive expression of cytokeratin 7 (CK7).

참고문헌 (Reference)

1 Mizusawa H, "Squamous cell carcinoma in the renal pelvis of a horseshoe kidney" 11 : 782-784, 2004

2 Akan H, "Mucinous cystadenoma mimicking simple renal parenchymal cyst in a horseshoe kidney" 12 : 493-496, 2005

3 Takehara K, "Mucinous adenocarcinoma of the renal pelvis associated with transitional cell carcinoma in the renal pelvis and the bladder" 11 : 1016-1018, 2004

4 Rubio Briones J, "Incidence of tumoural pathology in horseshoe kidneys" 33 : 175-179, 1998

5 Tamboli P, "Colonic adenocarcinoma metastatic to the urinary tract versus primary tumors of the urinary tract with glandular differentiation: a report of 7 cases and investigation using a limited immunohistochemical panel" 126 : 1057-1063, 2002

6 Spires SE, "Adenocarcinoma of renal pelvis" 117 : 1156-1160, 1993

7 Rajinder Jhobta, "Adenocarcinoma in Horseshoe Kidney" 연세대학교의과대학 44 (44): 744-746, 2003