Post-operative Infection Caused by Methicillin-Resistant Coagulase-Negative Staphylococci (MRCNS) in the Oral and Maxillofacial Region : A Case Report

다국어 초록 (Multilingual Abstract)

Osteomyelitis of the jaw infected with Coagulase-Negative Staphylococci (CNS) is rarely reported in the Oral and Maxillofacial Region. Staphylococcus is a part of the normal body flora, but it may be cause severe infections and coagulase-negative staphylococci are often described as the important pathogens in nosocomial infections. Although many studies on prevalence and antibiotics of Staphylococcus aureus have been done, but many of these studies focus only on Methicillin-resistant Staphylococcus aureus (MRSA) and not on Methicillin-resistant coagulase-negative Staphylococci (MRCNS). There was a less study about CNS or MRCNS infections in the Oral and Maxillofacial Region. This report describes a case of a 41-year-old male patient who developed osteomyelitis caused by methicillin-Resistant coagulase-Negative staphylococci (MRCNS) on condyle after ORIF and suggests guideline for the prevention of post-operative infection and appropriate recommendation for treatment and control.

참고문헌 (Reference)

1 Giulieri SG, "Using genomics to understand meticillin-and vancomycin-resistant Staphylococcus aureus infections" 6 : 000324-, 2020

2 황지희, "The Efficacy and Safety of Arbekacin and Vancomycin for the Treatment in Skin and Soft Tissue MRSA Infection: Preliminary Study" 대한감염학회 45 (45): 62-68, 2013

3 Sgarabotto D, "Synercid plus vancomycin for the treatment of severe methicillin-resistant Staphylococcus aureus and coagulase-negative staphylococci infections : evaluation of 5 cases" 34 : 122-126, 2002

4 Liu C, "Staphylococcus aureus with heterogeneous resistance to vancomycin: epidemiology, clinical significance, and critical assessment of diagnostic methods" 47 : 3040-3045, 2003

5 Newstead LL, "Staphylococcalproduced bacteriocins and antimicrobial peptides: their potential as alternative treatments for Staphylococcus aureus infections" 9 : E40-, 2020

6 Lourtet-Hascoët J, "Species and antimicrobial susceptibility testing of coagulase-negative staphylococci in periprosthetic joint infections" 146 : 1771-1776, 2018

7 Turabelidze G, "Personal hygiene and methicillin-resistant Staphylococcus aureus infection" 12 : 422-427, 2006

8 Álvarez A, "Methicillin-resistant Staphylococcus aureus in hospitals : latest trends and treatments based on bacteriophages" 57 : e01006-e01019, 2019

9 Lindsay JA, "Hospital-associated MRSA and antibiotic resistancewhat have we learned from genomics" 303 : 318-323, 2013

10 Morrow AJ, "Do postoperative antibiotics decrease the frequency of inflammatory complications following third molar removal" 76 : 700-708, 2018

11 Zweig BE, "Complications of mandibular fractures" 17 : 93-101, 2009

12 Nam KY, "Comparison of the most common isolates of postoperative endophthalmitis in South Korea;Enterococcus species vs coagulase-negative staphylococci" 16 : 706-, 2016

13 Carter TG, "Community acquired methicillin-resistant Staphylococcus aureus facial abscesses : case reports" 63 : 1021-1025, 2005

14 Becker K, "Coagulase-negative staphylococci" 27 : 870-926, 2014

15 Rogers KL, "Coagulase-negative staphylococcal infections" 23 : 73-98, 2009

16 Baur DA, "Chronic osteomyelitis of the mandible : diagnosis and management--an institution’s experience over 7 years" 73 : 655-665, 2015

17 Seng R, "Biofilm formation of methicillin-resistant coagulase negative staphylococci(MR-CoNS)isolated from community and hospital environments" 12 : e0184172-, 2017

18 Haeffs TH, "Acute and chronic suppurative osteomyelitis of the jaws : a 10-year review and assessment of treatment outcome" 76 : 2551-2558, 2018

19 Domingo F, "A single-center retrospective review of postoperative infectious complications in the surgical management of mandibular fractures : Postoperative antibiotics add no benefit" 81 : 1109-1114, 2016