四君子湯, 四物湯 및 八物湯이 筋肉疲勞恢復에 미치는 實驗的 硏究 = The Experimental Studies of Sagunjang, Samultang and Palmultang affecting the Recovery of Fatigue of Muscles

다국어 초록 (Multilingual Abstract)

The levels of exhausting sbustances in blood change under the concerns one another and make a difference according to the rate of exercise. As resources of energy, fattic acid, Keton body and glucose are used in muscle cells having a rest or working an average normal action. In addition to these ingredients, glycogen and phosphocreatine which are in the muscle cells are used during severe exercise. lactate, pyruvate and creatinine which are the products of fatigus are derived from this process.
The substances in blood concerning the fatigus of muscles are observed clinically in sports medicine. The fast reduction of these substances can help the recovery of muscular fatigus and the concerned disease as well as help do well the sports games especially reguired endurance and alertness. Therefore these experimental studies obtained several conclusions from two groups of white rats, that are under the same conditions that they are forced such a maximum swimming that they become extremely tired. Among them, normal saline is administered into one group, while the extracts of Sagunjatang(Sample A), Samultang(Sample B) and Palmultang(Sample C) are administered into the other.
The followings are the results of the results of the products of muscular fatigue in blood(lactate, pyruvate, creatinine) and of the metabolic substances(glucose, NEFA) according to time(30, 60, 120, 240 min) after the administration of these extracts.
1. One of the products of metabolism, lactate levels decrease in the rat under the administration of the extracts of Sagunjatang, Samultang and Palmultang in 60 minutes(p＜0.05).
2. Pyruvate levels decrease in the rat under the administration of these extracts in 60 minutes(p＜0.05).
3. Creatinine levels decrease significantly in the rat under the administration of all these extracts in 30minutes(p＜0.001), and decrease slightly in 4hrs(p＜0.05) under the administration of extracts of Sagunjatang and Samultang.
4. One of the metabolic substances, glucose livels in blood increase significantly in 60minutes(p＜0.05) under the adminstration of all these extracts.
5. NEFA levels also decrease in 60 minutes(p＜0.02) under the administration of the extracts of Sagunjatang, whereas they decrease in 2hrs(p＜0.01) under the administration of the extracts of Samultang and Palmultang.
According to the above results, administration of Bo-Chi(補氣), Bo-Hyul(補血), and Bo-Chihyul herb medicine(補氣血劑) has a good effect on the process of the recovery of fatigue of muscles. Even though the differences are in the rates, the use of Bo-Hyul herb medicine(補血劑) that the activation of Chi(氣) precedes can be good for the department of sports medicine as well as for the recovery of fatigue of muscles.